P9797

臭化ピリドスチグミン

• 別名: 3-(ジメチルアミノカルボニルオキシ)-1-メチルピリジニウム ブロミド
• 実験式（ヒル表記法）: C₉H₁₃BrN₂O₂
• CAS番号: 101-26-8
• 分子量: 261.12
• EC Number: 202-929-9
• MDL番号: MFCD00079283
• UNSPSCコード: 12352200
• PubChem Substance ID: 24277865
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• 品質水準: 100
• フォーム: solid
• 溶解性: water: 100 mg/mL, clear to very slightly hazy, colorless
• オーガナイザー: Valeant
• SMILES記法: [Br-].CN(C)C(=O)Oc1ccc[n+](C)c1
• InChI: 1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1
• InChI Key: VNYBTNPBYXSMOO-UHFFFAOYSA-M
• 遺伝子情報: human ... ACHE(43)

詳細

アプリケーション

Pyridostigmine bromide has been used as a cholinesterase inhibitor in mice, in florimetric assay for acetylcholine secretion and for measuring acetylcholine release from mice atrial tissue.

生物化学的／生理学的作用

アセチルコリンエステラ-ゼインヒビタ-。

Pyridostigmine bromide inhibits acetylcholine esterase and is membrane impermeable. It is used as a preventive medicine in chemical warfare. Pyridostigmine bromide is a carbamate compound comprising quaternary amine structure. It displays low absorption at the gastrointestinal tract. Sustained release of pyridostigmine is recommended for improving its bioavailability in treating myasthenia gravis.

特徴および利点

This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H300 + H310 + H330,H317
• 注意書き: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
• 危険有害性の分類: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Skin Sens. 1
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges