C0256

シチジン5′-ジホスホコリン ナトリウム塩 二水和物

~98%, from yeast, solid

• 別名: CDP-コリン, CDP-コリン-Na, P′-[2-(トリメチルアンモニオ)­エチル]­エステル シチジン 5′-(三水素二リン酸)分子内塩一ナトリウム, シチコリンナトリウム
• 実験式（ヒル表記法）: C₁₄H₂₅N₄NaO₁₁P₂ · 2H₂O
• CAS番号: 33818-15-4
• 分子量: 546.34
• Beilstein: 4110040
• MDL番号: MFCD00150508
• UNSPSCコード: 41106300
• PubChem Substance ID: 24278064
• NACRES: NA.77

特性

• 由来生物: yeast
• 品質水準: 200
• アッセイ: ~98%
• フォーム: solid
• 色: white
• 溶解性: H₂O: 100 mg/mL
• 保管温度: −20°C
• SMILES記法: [Na+].C[N+](C)(C)CCOP([O-])(=O)OP([O-])(=O)OCC1OC([C@H](O)[C@@H]1O)N2C=CC(N)=NC2=O
• InChI: 1S/C14H26N4O11P2.Na/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21;/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25);/q;+1/p-1/t9?,11-,12-,13?;/m1./s1
• InChI Key: YWAFNFGRBBBSPD-MBWJOHGMSA-M

詳細

詳細

Cytidine 5′-diphosphocholine (CDP-choline) contains cytidine and choline linked via a diphosphate bridge.

アプリケーション

Cytidine 5′-diphosphocholine sodium salt dihydrate has been used as a physiological metabolite for the identification of gemcitabine diphosphate choline (GdPC) by liquid chromatography-mass spectrometry (LC-MS/MS) method in the Kennedy pathway .

生物化学的／生理学的作用

Cytidine 5′-diphosphocholine (CDP-choline) plays an important role in the synthesis of phosphatidylcholine. It is also involved in the biosynthesis of acetylcholine, a neurotransmitter. CDP-choline has therapeutic effects against hypoxia, cerebral ischemia and traumatic brain injury. It also exhibits therapeutic effects against learning and memory disorders, drug addiction and Alzheimer′s and Parkinson′s diseases.

注意

吸湿性です。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)