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安全性情報

A9667

Sigma-Aldrich

Anti-Human IgE (ε-chain specific)−Peroxidase antibody produced in goat

IgG fraction of antiserum, buffered aqueous solution

別名:

Goat Anti-Human IgE (ε-chain specific)−HRP

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

goat

品質水準

結合体

peroxidase conjugate

抗体製品の状態

IgG fraction of antiserum

抗体製品タイプ

secondary antibodies

クローン

polyclonal

フォーム

buffered aqueous solution

テクニック

direct ELISA: 1:2,000
dot blot: 1:10,000 (chemiluminescent)

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

詳細

IgEs are glycoprotein antibodies that regulate immunological responses to allergies and infections. These immunoglobulins have been implicated in mediating Type I hypersensitivity reactions . Elevated IgE levels have been associated with hyper IgE syndrome and allergic asthma. Anti-Human IgE ε-chain specific-Peroxidase antibody binds to human IgE as against human IgG, and Bence Jones κ and λ myeloma proteins.
Immunoglobulin E (IgE) belongs to the immunoglobulin family and consists of epsilon(ε) heavy chain in the constant (C) region. IgE has a monomeric structure with an extra domain in the constant region.

免疫原

IgE purified from human myeloma serum

アプリケーション

Anti-Human IgE (ε-chain specific)-Peroxidase antibody produced in goat has been used in IgE immunoblotting and in western blotting to analyse IgE binding efficiency.

物理的形状

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 0.05% MIT

調製ノート

Avrameas, S., et al., Scand. J. Immunol., 8, Suppl. 7, 7 (1978)に記載の2段階グルタルアルデヒド法により作製しています。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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ピクトグラム

Health hazard

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Resp. Sens. 1 - Skin Sens. 1

保管分類コード

12 - Non Combustible Liquids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

A9667-VAR:
A9667-BULK:
IXO32160:
A9667-2ML:


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試験成績書(COA)

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文書ライブラリにアクセスする

Alok Kumar Verma et al.
Toxicology letters, 210(1), 24-33 (2012-01-31)
Allergy to chickpea or Garbanzo bean (Cicer arietinum) has been reported in the Indian population. Little information is found regarding allergenic events involved in the chickpea allergy; therefore, chickpea allergenicity assessment was undertaken. In vivo and ex vivo studies were
Amita Misra et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(10), 2725-2736 (2010-07-06)
We sought to assess the allergenic potential of red gram by identifying and characterizing the responsible proteins. Immunoblotting was performed to detect IgE binding proteins. Identities of these proteins were confirmed by mass spectrometry. To evaluate allergenic potential, BALB/c mice
Elvira Ruppel et al.
Chembiochem : a European journal of chemical biology, 11(16), 2283-2293 (2010-09-28)
Celery is a frequent cause of food allergy in pollen-sensitized patients and can induce severe allergic reactions. Clinical symptoms cannot be predicted by skin prick tests (SPTs) or by determining allergen-specific immunoglobulin E (IgE). Our aim was to identify specific
F Mutapi et al.
Parasite immunology, 33(3), 181-192 (2011-01-06)
Schistosoma haematobium antigen recognition profiles of the human isotypes IgA, IgE, IgG1 and IgG4 were compared by image analysis of western blots. Adult worm antigens separated by two-dimensional gel electrophoresis were probed with pooled sera from Zimbabweans resident in a
Amita Misra et al.
GM crops & food, 3(4), 273-282 (2012-06-30)
Genetically modified (GM) mustard line (V4) with increased carotenoid content was compared with native mustard to find the difference in allergenic potential, if any. Simulated gastric fluid (SGF) digestibility of crude protein extract from GM as well as its native

資料

Antibody-based serology tests are useful in identifying subjects with an adaptive immune response to the SARS-CoV-2 virus. Anti-human immunoglobulin antibodies allow for quick and simple, yet reliable assays with easy readouts and can also be adapted for high-throughput screening.

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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