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由来生物
mouse
品質水準
結合体
alkaline phosphatase conjugate
抗体製品の状態
purified from hybridoma cell culture
抗体製品タイプ
secondary antibodies
クローン
GE-1, monoclonal
形状
buffered aqueous solution
化学種の反応性
human
テクニック
direct ELISA: 1:6,000
dot blot: 1:1,000
アイソタイプ
IgG2b
輸送温度
wet ice
保管温度
2-8°C
ターゲットの翻訳後修飾
unmodified
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関連するカテゴリー
詳細
ヒトIgEと結合しますが、ヒトIgG、IgAまたはIgMとは結合しません。
IgEs are glycoprotein antibodies that regulate immunological responses to allergies and infections. These immunoglobulins have been implicated in mediating Type I hypersensitivity reactions. Elevated IgE levels have been associated with hyper IgE syndrome and allergic asthma.
Monoclonal Anti-Human IgE (mouse IgG2b isotype) is derived from the GE-1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
アプリケーション
キメラモノクローナル抗体がイプシロン鎖を有することを確認するため、1:1000希釈モノクローナル抗ヒトIgE抗体（clone GE1）を用いてELISAを実施しました。
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Mouse monoclonal anti-human IgE-alkaline phosphatase antibody has been used for :
- immunoblot assays
- direct ELISA
- dot blot
生物化学的／生理学的作用
IgEs are glycoprotein antibodies that regulate immunological responses to allergies and infections. These immunoglobulins have been implicated in mediating Type I hypersensitivity reactions. Elevated IgE levels have been associated with hyper IgE syndrome and allergic asthma.
物理的形状
Solution in 0.05 M Tris, pH 8.0, containing 1% bovine serum albumin, 1 mM MgCl2 and 15 mM sodium azide
アナリシスノート
本抗体は、骨髄腫IgEおよびアレルギーにより上昇したIgEに対する反応性について検証されています。
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
A3076-.5ML:
A3076-.2ML:
A3076-BULK:
A3076-VAR:
試験成績書（COA）
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Kyoung Yong Jeong et al.
Clinical and diagnostic laboratory immunology, 11(2), 320-324 (2004-03-12)
Chironomids are widely and abundantly distributed in the vicinity of standing waters. Larvae of Chironomus and some other genera are known to contain hemoglobins, which have been described as a major allergen, and the adults that have no hemoglobins also
Nathalie Acevedo et al.
PloS one, 8(11), e78353-e78353 (2013-11-14)
Helminth infections and allergy have evolutionary and clinical links. Infection with the nematode Ascaris lumbricoides induces IgE against several molecules including invertebrate pan-allergens. These antibodies influence the pathogenesis and diagnosis of allergy; therefore, studying parasitic and non-parasitic allergens is essential
A Diaz-Perales et al.
The Journal of allergy and clinical immunology, 102(1), 127-133 (1998-07-29)
Several foods associated with the latex-fruit syndrome present relevant allergens of around 30 kd. Neither these components nor any other responsible for the reported cross-reactions have been identified and purified. We sought to isolate and characterize the 30 kd allergens
Astrid R R Heutelbeck et al.
International archives of occupational and environmental health, 82(9), 1123-1131 (2009-02-25)
Cattle are an important source of allergens in the working area of farmers. Asthma caused by cow allergens is a significant occupational problem. Yet in allergological testing, the results of in vivo and in vitro diagnostic tests are often inconsistent
Marta Burzyńska et al.
Acta scientiarum polonorum. Technologia alimentaria, 19(1), 15-24 (2020-04-01)
Small amounts of protein can be found in honey, including well known allergen sources, such as plant pollen and honeybee secretions. Despite this, there are few case reports describing allergic reactions following the consumption of honey. The aim of this
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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