PHR1447

レベチラセタム

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: (αS)-α-エチル-2-オキソ-1-ピロリジンアセトアミド, 2(S)-(2-オキソピロリジン-1-イル)ブチルアミド
• 実験式（ヒル表記法）: C₈H₁₄N₂O₂
• CAS番号: 102767-28-2
• 分子量: 170.21
• MDL番号: MFCD03265610
• UNSPSCコード: 41116107
• PubChem Substance ID: 329822607
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. Y0001253; traceable to USP 1359404
• APIファミリー: levetiracetam
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-8°C
• SMILES記法: CC[C@H](N1CCCC1=O)C(N)=O
• InChI: 1S/C8H14N2O2/c1-2-6(8(9)12)10-5-3-4-7(10)11/h6H,2-5H2,1H3,(H2,9,12)/t6-/m0/s1
• InChI Key: HPHUVLMMVZITSG-LURJTMIESA-N
• 遺伝子情報: human ... CACNA1B(774) , SV2A(9900)

詳細

詳細

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Levitiracetam, an analog of piracetam, is an antiepileptic drug widely used for the remedy of epileptic seizures, partial as well as generalized epilepsy.

アプリケーション

Levitiracetam may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques and spectrofluorimetric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

レベチラセタムは、抗てんかん作用のあるピロリジンです。レベチラセタムの立体選択的結合は、中枢神経系におけるシナプス細胞膜に限定され、末梢組織での結合はみられません。レベチラセタムは、通常の神経興奮性に影響を与えずにバースト発火を抑制します。このことから、てんかん様のバースト発火の過同期および発作の伝達を選択的に抑制している可能性があります。

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAA2824 in the slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable