900600

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid

≥95%

• 別名: Carboxyl sulfonyl fluoride alkyne, Probe building block
• 実験式（ヒル表記法）: C₁₂H₁₃FO₄SSi
• CAS番号: 2088829-06-3
• 分子量: 300.38
• MDL番号: MFCD30737995
• UNSPSCコード: 12352106
• NACRES: NA.22

特性

• アッセイ: ≥95%
• 形状: solid
• 反応適合性: reagent type: cross-linking reagent
• 利用可能性: available only in USA
• 保管温度: −20°C
• SMILES記法: O=S(C1=CC(C#C[Si](C)(C)C)=CC(C(O)=O)=C1)(F)=O

詳細

アプリケーション

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

その他情報

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

安全性情報

• ピクトグラム: GHS02,GHS07
• シグナルワード: Danger
• 危険有害性情報: H242,H315,H319
• 注意書き: P210 - P235 - P302 + P352 - P305 + P351 + P338 - P370 + P378 - P403
• 危険有害性の分類: Eye Irrit. 2 - Self-react. C - Skin Irrit. 2
• 保管分類コード: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable