M9140

Methylene blue

Dye content, ≥82%, certified by the Biological Stain Commission, powder

• Sinonimo/i: Basic Blue 9, 3,7-bis(Dimethylamino)phenazathionium chloride, Tetramethylthionine chloride
• Formula empirica (notazione di Hill): C₁₆H₁₈ClN₃S · xH₂O
• Numero CAS: 122965-43-9
• Peso molecolare: 319.85 (anhydrous basis)
• Colour Index: 52015
• Beilstein: 3599847
• Numero CE: 200-515-2
• Numero MDL: MFCD00150006
• Codice UNSPSC: 12171500
• ID PubChem: 24897317
• NACRES: NA.47

Proprietà

• product name: Methylene blue, certified by the Biological Stain Commission
• Grado: certified by the Biological Stain Commission
• Livello qualitativo: 200
• Forma fisica: powder
• Composizione: Dye content, ≥82%
• Colore: dark green
• Solubilità: H₂O: 4mg/4ml
• applicazioni: diagnostic assay manufacturing; hematology; histology
• Temperatura di conservazione: room temp
• Stringa SMILE: CN(C)C1=CC=C2C(SC(C3=N2)=CC(C=C3)=[N+](C)C)=C1.[H]O[H].[Cl-]
• InChI: 1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1; WQVSELLRAGBDLX-UHFFFAOYSA-M
• Informazioni sul gene: human ... CYP1A2(1544) , GSR(2936)

Descrizione

Descrizione generale

Methylene blue is a compound that occurs as crystals or crystalline powder, having a bronze-like luster. It is soluble in water, chloroform and partially soluble in alcohol. It is a photoactive dye, which is a member of phenothiazine family.

Applicazioni

Methylene blue has been used:

• to stain vaginal cells
• for the preparation of protein aqueous ink
• to evaluate cell survival by staining

Azioni biochim/fisiol

Methylene blue is used as a bacteriologic stain or dye and indicator. It mediates the inactivation of enveloped viruses in plasma, when exposed to visible light. It is an inhibitor of nitric oxide synthase and guanylate cyclase. It also plays a key role in medicine as an antimalarial agent, reducing agent in methemoglobinemia and inducer of apoptosis in cancer cells.

Compatibilità

Certified for use in Mallory′s phloxine-methylene blue stain; Levine & Black stain for bacteria in milk; Wright stain for blood smears.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P264 - P270 - P301 + P312 - P501
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves