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319112

Sigma-Aldrich

Methylene Blue solution

0.05 wt. % in H2O

Sinonimo/i:

Loeffler’s Methylene Blue

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About This Item

Formula empirica (notazione di Hill):
C16H18ClN3S
Numero CAS:
61-73-4
Peso molecolare:
319.85
Colour Index:
52015
Beilstein:
3641570
Numero MDL:
MFCD00012111
Codice UNSPSC:
12171500
ID PubChem:
24858888
NACRES:
NA.47

Forma fisica

liquid

Livello qualitativo

200

Concentrazione

0.05 wt. % in H2O

Densità

0.98 g/mL at 25 °C

λmax

665 nm

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

[Cl-].CN(C)c1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](/C)C

InChI

1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1
CXKWCBBOMKCUKX-UHFFFAOYSA-M

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Applicazioni

Methylene Blue solution has been used to study structural alterations and p53 immune-expression in rats.

Azioni biochim/fisiol

Methylene blue (MB) is a highly recognized histological dye. It plays a vital role in microbiology and pharmacology. It has been employed in staining living organisms and in methemoglobinemia treatment. MB exhibits maximum absorption at 664nm. Exposure to methylene blue leads to various health hazards such as increased heart rate, vomiting, shock, Heinz body formation, cyanosis, jaundice, quadriplegia and tissue necrosis in humans

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
MKCK4473
MKCD3437
MKBX9824V
MKBV9924V
MKBQ6919V

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Methylene blue in photodynamic therapy: From basic mechanisms to clinical applications.
Tardivo JP
Photodiagnosis and Photodynamic Therapy, 2, 175-191 (2005)
Microscopic structural alterations
and p53 immune-expression in adult
rat testis in response to intra-tunical versus
intra-parenchymal injection of methylene blue
Mazroa S A
International Journal of Clinical and Experimental Pathology, 9, 5346-5356 (2016)
Alexandru Grigoroiu et al.
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Hyperspectral imaging (HSI) is being explored in endoscopy as a tool to extract biochemical information that may improve contrast for early cancer detection in the gastrointestinal tract. Motion artefacts during medical endoscopy have traditionally limited HSI application, however, recent developments
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With the debate over extent of lymphadenectomy in endometrial cancer, sentinel lymph node (SLN) mapping may provide a focused approach to evaluate the most relevant lymph nodes (LN) while minimizing the complications. We evaluated SLN mapping using filtered technetium(99), indocyanine
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Transcription initiation involves the coordinated activities of large multimeric complexes, but little is known about their biogenesis. Here we report several principles underlying the assembly and topological organization of the highly conserved SAGA and NuA4 co-activator complexes, which share the
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