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N6125

Sigma-Aldrich

Naphthol AS-TR phosphate disodium salt

fluorogenic, ≥99% (HPLC), powder

Sinônimo(s):

NASTRp disodium salt

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About This Item

Fórmula empírica (Notação de Hill):
C18H13ClNNa2O5P
Número CAS:
4264-93-1
Peso molecular:
435.71
Número MDL:
MFCD00069550
Código UNSPSC:
12352204
ID de substância PubChem:
24897766
NACRES:
NA.83

Nome do produto

Naphthol AS-TR phosphate disodium salt, ≥99% (HPLC), Bulk package

Ensaio

≥99% (HPLC)

Formulário

powder

solubilidade

water: 50 mg/mL, clear, colorless to faintly yellow

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[Na+].[Na+].Cc1cc(Cl)ccc1NC(=O)c2cc3ccccc3cc2OP([O-])([O-])=O

InChI

1S/C18H15ClNO5P.2Na/c1-11-8-14(19)6-7-16(11)20-18(21)15-9-12-4-2-3-5-13(12)10-17(15)25-26(22,23)24;;/h2-10H,1H3,(H,20,21)(H2,22,23,24);;/q;2*+1/p-2

chave InChI

TYCHZTPSWMGRRI-UHFFFAOYSA-L

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Aplicação

Substrate for the histochemical demonstration of acid and alkaline phosphatase.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
SLCL9258
SLCG1650
SLCC8157
SLBW1877
SLBS8237

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Adéla Kratochvílová et al.
Scientific reports, 10(1), 7489-7489 (2020-05-06)
Caspases are proteases traditionally associated with inflammation and cell death. Recently, they have also been shown to modulate cell proliferation and differentiation. The aim of the current research was to search for osteogenic molecules affected by caspase inhibition and to specify
Eva Svandova et al.
Journal of anatomy, 235(2), 256-261 (2019-05-31)
FASL (CD178) is known for its role in triggering apoptosis, mostly in relation with immune cells but additional functions have been reported more recently, including those in bone development. Examination of postnatal FasL-deficient mice (gld) showed an increased bone deposition
Claire Chevalier et al.
STAR protocols, 2(2), 100452-100452 (2021-04-30)
Mesenchymal-derived osteoblasts play a key role in bone formation via synthesis and mineralization of the bone and bone remodeling. Osteoclasts are multinucleated cells of hematopoietic origin with a role in bone resorption. Here, we describe a protocol for generating primary
Veronika Oralová et al.
Biology open, 8(5) (2019-05-28)
Zebrafish is now widely used in biomedical research as a model for human diseases, but the relevance of the model depends on a rigorous analysis of the phenotypes obtained. Many zebrafish disease models, experimental techniques and manipulations take advantage of
Claire Chevalier et al.
Cell metabolism, 32(4), 575-590 (2020-09-12)
Osteoporosis is the most prevalent metabolic bone disease, characterized by low bone mass and microarchitectural deterioration. Here, we show that warmth exposure (34°C) protects against ovariectomy-induced bone loss by increasing trabecular bone volume, connectivity density, and thickness, leading to improved
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Colorimetric Alkaline Phosphatase and Peroxidase Substrate Detection Systems

Nitroblue Tetrazolium (NBT) is used with the alkaline phosphatase substrate 5-Bromo- 4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures. These substrate systems produce an insoluble NBT diformazan end product that is blue to purple in color and can be observed visually.

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