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Merck
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Key Documents

H0501

Sigma-Aldrich

DL-Homocystine

Sinônimo(s):

meso-4,4′-Dithio-bis(2-aminobutanoic acid)

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About This Item

Fórmula linear:
HOOCCH(NH2)CH2CH2SSCH2CH2CH(NH2)COOH
Número CAS:
Peso molecular:
268.35
Beilstein:
1728581
Número CE:
Número MDL:
Código UNSPSC:
12352209
eCl@ss:
42021308
ID de substância PubChem:
NACRES:
NA.26

Ensaio

≥98% (TLC)

Nível de qualidade

forma

powder

cor

white to off-white

pf

>300 °C

aplicação(ões)

detection

cadeia de caracteres SMILES

N[C@H](CCSSCC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/t5-,6+

chave InChI

ZTVZLYBCZNMWCF-OLQVQODUSA-N

Informações sobre genes

human ... BHMT(635)

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Categorias relacionadas

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


Certificados de análise (COA)

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Lei Li et al.
Amino acids, 50(10), 1485-1494 (2018-08-01)
Plasma homocysteine is elevated in patients with impaired renal function, and markedly so at end-stage renal disease. As chronic kidney disease and hyperhomocysteinemia are also independent risk factors for cardiovascular disease, the latter is hypothesized to accelerate vascular abnormalities following
Sezgin Bakirdere et al.
Analytica chimica acta, 680(1-2), 41-47 (2010-10-26)
An analytical method was developed for the determination of thiols in biological samples. Reverse phase chromatography coupled to ICP quadrupole MS or Orbitrap MS was employed for the separation and detection of thiols. For the determination of total thiols, oxidized
Chasity B Love-Nkansah et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 22(3), 934-940 (2015-11-05)
Homocysteine sulfinyl radical ((SO⋅) Hcy) is a reactive intermediate involved during oxidative damage of DNA in the presence of high concentrations of homocysteine (Hcy). The short lifetime of (SO⋅) Hcy makes its preparation, isolation, and characterization challenging using traditional chemical
M W Orth et al.
The Journal of nutrition, 122(3), 482-487 (1992-03-01)
The effect of excessive levels of cysteine and homocysteine on tibial dyschondroplasia (TD) in broiler chicks was studied. In the first experiment, graded levels of L-cysteine as well as one level of L-homocysteine were supplemented to a corn-soybean-based diet adequate
Javier Escobar et al.
Journal of pharmaceutical and biomedical analysis, 123, 104-112 (2016-02-20)
The aminothiols are biological compounds with numerous vital functions. One of the most relevant is their role as antioxidant systems. The reduced to oxidized ratios are extremely useful indicators of oxidative stress and cellular redox status. We have validated an

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