H4628

DL-Homocysteine

≥95% (titration)

• Sinônimo(s): 2-Amino-4-mercaptobutyric acid
• Fórmula linear: HSCH₂CH₂CH(NH₂)COOH
• Número CAS: 454-29-5
• Peso molecular: 135.18
• Beilstein: 1721683
• Número CE: 207-222-9
• Número MDL: MFCD00004898
• Código UNSPSC: 12352209
• eCl@ss: 42021308
• ID de substância PubChem: 24895646
• NACRES: NA.26

Propriedades

• Nome do produto: DL-Homocysteine, ≥95% (titration)
• Nível de qualidade: 200
• Ensaio: ≥95% (titration)
• Formulário: powder
• pf: 232-233 °C (lit.)
• solubilidade: H₂O: soluble
• aplicação(ões): cell analysis; peptide synthesis
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: NC(CCS)C(O)=O
• InChI: 1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)
• chave InChI: FFFHZYDWPBMWHY-UHFFFAOYSA-N

Descrição

Aplicação

DL-Homocysteine has been used to induce hyperhomocysteinemia in Sprague–Dawley rats. It has also been used to study the effects of hyperhomocysteinemia on atherosclerosis in apolipoprotein E-deficient mice.

Ações bioquímicas/fisiológicas

Homocysteine is a sulfhydryl-containing amino acid, synthesized from methionine. It is a non-essential, non-proteinogenic amino acid. It is an important determinant of the methylation cycle and is present in the plasma in four forms. An abnormally high level of homocysteine leads to hyperhomocysteinemia and also promotes atherosclerosis.

Increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis; may be a marker for tumor cell growth.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)