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C5360

SAFC

L-cisteína

Fabricação farmacêutica

Sinônimo(s):

Ácido (R)-2-amino-3-mercaptopropiônico

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About This Item

Fórmula linear:
HSCH2CH(NH2)CO2H
Número CAS:
52-90-4
Peso molecular:
121.16
Beilstein:
1721408
Número CE:
200-158-2
Número MDL:
MFCD00064306
Código UNSPSC:
12352209
eCl@ss:
32160406
NACRES:
NA.26

fonte biológica

non-animal source

Nível de qualidade

400

forma

crystalline powder

técnica(s)

cell culture | mammalian: suitable

Impurezas

endotoxin, heavy metals, trace metals, tested

pf

240 °C (dec.) (lit.)

solubilidade

H2O: 25 mg/mL

adequação

suitable for manufacturing use

atividade externa

cytotoxicity, tested

cadeia de caracteres SMILES

N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1

chave InChI

XUJNEKJLAYXESH-REOHCLBHSA-N

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Categorias relacionadas

Descrição geral

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Aplicação

L-Cysteine is a non-essential amino acid. It is commonly used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Ações bioquímicas/fisiológicas

Agonista de receptor glutamatérgico de NMDA.

Informações legais

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Ácido L-aspártico

SAFC

A5474

Ácido L-aspártico

L-Cysteine, Free Base Naturally-occurring non-essential amino acid.

Millipore

243005

L-Cysteine, Free Base

L-Arginina

SAFC

A4474

L-Arginina

L-cisteína from non-animal source, suitable for cell culture, meets EP, USP testing specifications

Sigma-Aldrich

C6852

L-cisteína

D-Cysteine ≥99% (RT)

Sigma-Aldrich

30095

D-Cysteine

L-Tyrosine

SAFC

T4321

L-Tyrosine

Nicholas Kwiatkowski et al.
Nature, 511(7511), 616-620 (2014-07-22)
Tumour oncogenes include transcription factors that co-opt the general transcriptional machinery to sustain the oncogenic state, but direct pharmacological inhibition of transcription factors has so far proven difficult. However, the transcriptional machinery contains various enzymatic cofactors that can be targeted
Eun Young Park et al.
Journal of agricultural and food chemistry, 62(26), 6183-6189 (2014-06-01)
The present study examined the impact of the supplementation of glutathione (GSH), γ-L-glutamyl-L-cysteinyl-glycine, on human blood GSH levels. Healthy human volunteers were orally supplemented with GSH (50 mg/kg body weight). Venous blood was collected from the cubital vein before and
Aurelie Kas et al.
Brain : a journal of neurology, 137(Pt 7), 2077-2087 (2014-05-03)
Kleine-Levin syndrome is characterized by relapsing-remitting episodes of severe hypersomnia, cognitive impairment, apathy, derealization and behavioural disturbances. Between episodes, patients have normal sleep, mood and behaviour. Functional imaging studies performed in small series of patients with Kleine-Levin syndrome with visual
Takeshi Annoura et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(5), 2158-2170 (2014-02-11)
The 10 Plasmodium 6-Cys proteins have critical roles throughout parasite development and are targets for antimalaria vaccination strategies. We analyzed the conserved 6-cysteine domain of this family and show that only the last 4 positionally conserved cysteine residues are diagnostic
John Gilchrist et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(51), E5016-E5024 (2013-12-04)
Voltage-gated sodium (Nav) channels are embedded in a multicomponent membrane signaling complex that plays a crucial role in cellular excitability. Although the mechanism remains unclear, β-subunits modify Nav channel function and cause debilitating disorders when mutated. While investigating whether β-subunits
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Chromatograms

application for HPLC

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