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Documentos Principais

T4321

SAFC

L-Tyrosine

Sinônimo(s):

(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-L-alanine

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About This Item

Fórmula linear:
4-(HO)C6H4CH2CH(NH2)CO2H
Número CAS:
Peso molecular:
181.19
Beilstein:
392441
Número CE:
Número MDL:
Código UNSPSC:
12352209
eCl@ss:
32160406

fonte biológica

non-animal source

Ensaio

≥99%

Formulário

crystalline powder

técnica(s)

cell culture | mammalian: suitable

Impurezas

endotoxin, heavy metals, trace metals, residual solvents, tested

pf

>300 °C (dec.) (lit.)

solubilidade

1 M HCl: 25 mg/mL

aplicação(ões)

pharmaceutical (small molecule)

atividade externa

cytotoxicity, tested

cadeia de caracteres SMILES

N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1

chave InChI

OUYCCCASQSFEME-QMMMGPOBSA-N

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Descrição geral

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

Aplicação

L-Tyrosine is a non-essential amino acid with a polar side group. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Outras notas

Amino acid precursor of dopamine and other catecholamines

Informações legais

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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Proceedings of the National Academy of Sciences of the United States of America, 110(19), 7690-7695 (2013-04-20)
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The inflammasome adaptor ASC contributes to innate immunity through the activation of caspase-1. Here we found that signaling pathways dependent on the kinases Syk and Jnk were required for the activation of caspase-1 via the ASC-dependent inflammasomes NLRP3 and AIM2.
Verena Rahm et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(4), 546-550 (2014-02-26)
Low-grade gliomas (LGGs) may harbor malignant foci, which are characterized by increased tumor cellularity and angiogenesis. We used diffusion-weighted MR imaging (apparent diffusion coefficient [ADC]) and PET with the amino acid O-(2-(18)F-fluorethyl)-L-tyrosine ((18)F-FET) to search for focal changes of diffusion
Alena Volgusheva et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(18), 7223-7228 (2013-04-17)
Photobiological H2 production is an attractive option for renewable solar fuels. Sulfur-deprived cells of Chlamydomonas reinhardtii have been shown to produce hydrogen with the highest efficiency among photobiological systems. We have investigated the photosynthetic reactions during sulfur deprivation and H2
Bart Pennings et al.
The American journal of clinical nutrition, 98(1), 121-128 (2013-05-03)
Older individuals generally experience a reduced food-chewing efficiency. As a consequence, food texture may represent an important factor that modulates dietary protein digestion and absorption kinetics and the subsequent postprandial protein balance. We assessed the effect of meat texture on

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