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Documentos Principais

30552

Supelco

Monensin methyl ester

Selectophore, ≥97.0% (TLC)

Sinônimo(s):

Methyl monensin

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About This Item

Fórmula empírica (Notação de Hill):
C37H64O11
Número CAS:
Peso molecular:
684.90
Beilstein:
3641733
Código UNSPSC:
26111700
NACRES:
NB.61

grau

for ion-selective electrodes

Nível de qualidade

linha de produto

Selectophore

Ensaio

≥97.0% (TLC)

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC[C@]1(CCC(O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)C(O3)[C@@H](C)[C@@H](OC)[C@H](C)C(=O)OC)O2)C4OC(C[C@@H]4C)C5O[C@@](O)(CO)[C@H](C)C[C@@H]5C

InChI

1S/C37H64O11/c1-11-35(32-21(3)17-27(44-32)29-20(2)16-22(4)37(41,19-38)47-29)13-12-28(45-35)34(8)14-15-36(48-34)18-26(39)23(5)31(46-36)24(6)30(42-9)25(7)33(40)43-10/h20-32,38-39,41H,11-19H2,1-10H3/t20-,21+,22+,23+,24+,25+,26-,27-,28+,29-,30-,31-,32-,34+,35-,36+,37-/m0/s1

chave InChI

PFRZSHIENRKVSE-RJTHVKINSA-N

Descrição geral

Monensin, is an antibiotic produced by Streptomyces cinnamonensis. It is a naturally occurring ionophore. It has an acyclic polyether sequence and a terminal carboxylic acid moiety. It has the ability to effectively carry protons and cations through the cell membrane, hence it adequately harbours Na+ into a characteristic pseudoactivity, thereby effectively transporting it across a bio-membrane. It also forms stable complexes with k+, Rb+ and Ag+; hence it can be chemically modified to form cation-binding sites, thereby attaining transport functionalities.
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Aplicação


  • The selectivity of membrane ion-selective electrodes: This research explores the use of temperature variations to adjust the selectivity of ion-selective electrodes, utilizing Monensin methyl ester as a key component for sodium ion detection (Zahran et al., 2010).

  • Spectroscopic and semiempirical studies of a proton channel formed by the methyl ester of monensin A.: This paper presents a detailed analysis of the proton channel properties of Monensin methyl ester through spectroscopic and computational methods, highlighting its potential in analytical chemistry applications (Huczyński et al., 2006).

  • Ion chromatography detector based on solid-state ion-selective electrode array.: The development of an ion chromatography detector employing solid-state ion-selective electrodes, with Monensin methyl ester playing a crucial role in sodium ion detection, is detailed in this study (Lee et al., 2000).

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Informações legais

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

Pictogramas

Skull and crossbones

Palavra indicadora

Danger

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Adam Huczyñski et al.
The journal of physical chemistry. B, 110(31), 15615-15623 (2006-08-04)
Monensin A is an ionophore able to carry protons and cations through the cell membrane. Its methyl ester (MON1) and its hydrates have been studied in acetonitrile, and its deuterated analogue by Fourier transform infrared (FTIR) and (1)H and (13)C
Zum Funktionsprinzip von Elektrodenmembranen mit dem Carboxyl-Ionophoren Monensin an Festkontaktsensoren
J.G. Schindler , M.M. Schindler
Fresenius Journal of Analytical Chemistry, 332, 52-57 (1988)
[Monensin, an electrically charged carboxyl ionophor, and its neutral methylester as ion active components for Na+ selective disk electrodes].
J G Schindler et al.
Biomedizinische Technik. Biomedical engineering, 32(1-2), 22-24 (1987-01-01)
Adam Huczyński et al.
Biopolymers, 81(4), 282-294 (2005-11-29)
Monensin A methyl ester (MON1) was synthesized by a new method and its ability to form complexes with Li+, Na+, and K+ cations was studied by electrospray ionization-mass spectroscopy (ESI-MS), 1H and 13C nuclear magnetic resonance (NMR), Fourier transform infrared
Spectroscopic and semiempirical studies of a proton channel formed by the methyl ester of monensin A.
Huczynski A
The Journal of Physical Chemistry B, 110 (31), 15615-15623 (2006)

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