1.00090

Adipic acid

EMPROVE^® ESSENTIAL, Ph. Eur., NF

• Sinônimo(s): Adipic acid, Hexanedioic acid
• Fórmula empírica (Notação de Hill): C₆H₁₀O₄
• Número CAS: 124-04-9
• Peso molecular: 146.14
• Número MDL: MFCD00004420
• Código UNSPSC: 12352106
• Número E: E355
• Número do índice EC: 204-673-3

Propriedades

• Agency: NF; Ph. Eur.
• Nível de qualidade: 500
• conformidade reg.: FCC
• pressão de vapor: 0.097 hPa ( 18.5 °C)
• descrição: EMPROVE^® ESSENTIAL Ph Eur,NF,FCC,E 355
• linha de produto: EMPROVE^® ESSENTIAL
• Formulário: solid
• temperatura de autoignição: 405 °C
• potência: 5700 mg/kg LD₅₀, oral (Rat); >7940 mg/kg LD₅₀, skin (Rabbit)
• técnica(s): API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• pH: 2.7 (25 °C, 23 g/L in H₂O)
• pf: 150.9 °C
• temperatura de transição: flash point 196 °C
• solubilidade: 15 g/L
• densidade: 1.36 g/cm³ at 25 °C
• aplicação(ões): liquid formulation; pharmaceutical; solid formulation
• temperatura de armazenamento: 15-25°C
• InChI: 1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)
• chave InChI: WNLRTRBMVRJNCN-UHFFFAOYSA-N

Descrição

Descrição geral

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicação

Adipic acid is typically used as a pH modifier in pharmaceutical applications.

Informações legais

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS05
• Palavra indicadora: Danger
• Frases de perigo: H318
• Declarações de precaução: P280 - P305 + P351 + P338
• Classificações de perigo: Eye Dam. 1
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 384.8 °F - closed cup
• Ponto de fulgor (°C): 196 °C - closed cup