764191

Alkyne-PEG5-N-hydroxysuccinimidyl ester

• Sinônimo(s): Acetylene-PEG5-NHS ester, Alkyne-PEG5-NHS ester, Alkyne-PEG5-succinimidyl ester
• Fórmula empírica (Notação de Hill): C₁₈H₂₇NO₉
• Peso molecular: 401.41
• Número MDL: MFCD22574798
• Código UNSPSC: 12352108
• ID de substância PubChem: 329767105
• NACRES: NA.22

Propriedades

• forma: liquid
• Nível de qualidade: 100
• adequação da reação: reaction type: click chemistry; reagent type: cross-linking reagent
• grupo funcional: NHS ester; alkyne
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: C#CCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
• InChI: 1S/C18H27NO9/c1-2-6-23-8-10-25-12-14-27-15-13-26-11-9-24-7-5-18(22)28-19-16(20)3-4-17(19)21/h1H,3-15H2
• chave InChI: ACZDUKRWTPZVRP-UHFFFAOYSA-N

Descrição

Aplicação

Heterobifunctional crosslinker enabling the connection of an azide containing compound or biomolecule to one with a primary amine. The succinimidyl ester group will react preferentially with primary amines to form a covalent adduct and the terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification amine containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable