QBD10505

Azido-dPEG^®₁₂-NHS ester

• Sinônimo(s): Polyethylene glycol
• Fórmula empírica (Notação de Hill): C₃₁H₅₆N₄O₁₆
• Peso molecular: 740.79
• Número MDL: MFCD13184947
• Código UNSPSC: 12352108
• ID de substância PubChem: 329823933
• NACRES: NA.22

Propriedades

• Ensaio: >90%
• Formulário: solid or viscous liquid
• adequação da reação: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• arquitetura do polímero: shape: linear; functionality: heterobifunctional
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])ON1C(CCC1=O)=O
• chave InChI: JSNJRDFOCXNHTB-UHFFFAOYSA-N

Descrição

Características e benefícios

The azido-dPEG^®₁₂-NHS ester contains an azide function on one end of a single molecular weight dPEG^® spacer (47.2 Å) and NHS ester group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. N-hydroxysuccinimide (NHS) ester readily reacts with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Informações legais

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable