638455
Trifluoromethanesulfonamide
95%
Sinônimo(s):
1,1,1-Trifluoromethanesulfonamide, Trifluoromethylsulfonamide
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About This Item
Fórmula linear:
CF3SO2NH2
Número CAS:
Peso molecular:
149.09
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22
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Categorias relacionadas
Aplicação
Trifluoromethanesulfonamide can undergo reaction with paraformaldehyde either in sulfuric acid to give the corresponding open chain and cyclic condensation products or in ethyl acetate to give the corresponding oxy-methylated products.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Órgãos-alvo
Respiratory system
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
dust mask type N95 (US), Eyeshields, Gloves
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C J Lynch et al.
The Biochemical journal, 310 ( Pt 1), 197-202 (1995-08-15)
The role of carbonic anhydrase in de novo lipid synthesis was examined by measuring [1-14C]acetate incorporation into total lipids, fatty acids and non-saponifiable lipids in freshly isolated rat hepatocytes. Two carbonic anhydrase inhibitors, trifluoromethylsulphonamide (TFMS) and ethoxozolamide (ETZ) decreased incorporation
"Oxymethylation of trifluoromethanesulfonamide with paraformaldehyde in ethyl acetate"
Meshcheryakov.I.V, et al.
Russ. J. Org. Chem., 44(02), 311-316 (2008)
Marine Soulié et al.
Physical chemistry chemical physics : PCCP, 18(43), 29999-30008 (2016-11-03)
The arrangement of an ionic fluorophore in the crystalline state was regulated by the presence of various counter-ions and the effect on spectroscopic and self-association properties was studied. To do so, nine salts of berberine (i.e. a fluorescent natural alkaloid)
"Cascade transformations of trifluoromethanesulfonamide in reaction with formaldehyde"
Meshcheryakov.I.V, et al.
Russ. J. Org. Chem., 41(09), 1381-1386 (2005)
Lina Baranauskienė et al.
BMC biophysics, 5, 12-12 (2012-06-09)
Human carbonic anhydrases (CAs) play crucial role in various physiological processes including carbon dioxide and hydrocarbon transport, acid homeostasis, biosynthetic reactions, and various pathological processes, especially tumor progression. Therefore, CAs are interesting targets for pharmaceutical research. The structure-activity relationships (SAR)
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