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61250

Sigma-Aldrich

DL-Kynurenine

≥95.0% (NT), for peptide synthesis

Sinônimo(s):

2-Amino-3-(2-aminobenzoyl)propionic acid, 2-Amino-4-(2-aminophenyl)-4-oxobutyric acid

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About This Item

Fórmula empírica (Notação de Hill):
C10H12N2O3
Número CAS:
343-65-7
Peso molecular:
208.21
Beilstein:
2697333
Número CE:
206-445-9
Número MDL:
MFCD00025194
Código UNSPSC:
12352209
ID de substância PubChem:
57651839
NACRES:
NA.22

Nome do produto

DL-Kynurenine, ≥95.0% (NT)

Nível de qualidade

100

Ensaio

≥95.0% (NT)

Formulário

powder

pf

~235 °C (dec.)

aplicação(ões)

peptide synthesis

cadeia de caracteres SMILES

NC(CC(=O)c1ccccc1N)C(O)=O

InChI

1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)

chave InChI

YGPSJZOEDVAXAB-UHFFFAOYSA-N

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
BCCG4883
BCCD4177
BCCB3874
BCBW1489
BCBS2662V

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Poly(vinyl sulfate) potassium salt average Mw ~170,000

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5-Hydroxy-L-tryptophan 98% (calc. on dried substance)

Sigma-Aldrich

107751

5-Hydroxy-L-tryptophan

Adam K Walker et al.
Molecular psychiatry, 24(10), 1523-1532 (2018-07-11)
Inflammation activates indoleamine 2,3-dioxygenase (IDO) which metabolizes tryptophan into kynurenine. Circulating kynurenine is transported into the brain by the large amino transporter LAT1 at the level of the blood-brain barrier. We hypothesized that administration of leucine that has a high
Ye Lu et al.
Journal of clinical biochemistry and nutrition, 58(3), 210-215 (2016-06-04)
Postoperative fatigue syndrome is a general complication after surgery. However, there is no ''gold standard'' for fatigue assessment due to the lack of objective biomarkers. In this study, a rodent model of postoperative fatigue syndrome based on partial hepatectomy was
Alban Bessede et al.
Nature, 511(7508), 184-190 (2014-06-17)
Disease tolerance is the ability of the host to reduce the effect of infection on host fitness. Analysis of disease tolerance pathways could provide new approaches for treating infections and other inflammatory diseases. Typically, an initial exposure to bacterial lipopolysaccharide
László Vécsei et al.
Nature reviews. Drug discovery, 12(1), 64-82 (2012-12-15)
Various pathologies of the central nervous system (CNS) are accompanied by alterations in tryptophan metabolism. The main metabolic route of tryptophan degradation is the kynurenine pathway; its metabolites are responsible for a broad spectrum of effects, including the endogenous regulation
Soo Ching Lee et al.
Scientific reports, 8(1), 14277-14277 (2018-09-27)
We explored the gut microbiota profile among HIV-infected individuals with diverse immune recovery profiles following long-term suppressive ART and investigated the relationship between the altered bacteria with markers of immune dysfunction. The microbiota profile of rectal swabs from 26 HIV-infected
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