249505

2,6-Di-tert-butyl-4-methylpyridine

98%

• Sinônimo(s): 2,6-Bis(1,1-dimethylethyl)-4-methylpyridine, 2,6-Bis(tert-butyl)-4-methylpyridine, 2,6-Ditert-butyl-4-methylpyridine, 4-Methyl-2,6-di-tert-butylpyridine
• Fórmula empírica (Notação de Hill): C₁₄H₂₃N
• Número CAS: 38222-83-2
• Peso molecular: 205.34
• Beilstein: 130503
• Número CE: 253-834-4
• Número MDL: MFCD00006305
• Código UNSPSC: 12352100
• ID de substância PubChem: 24855001
• NACRES: NA.22

Propriedades

• Ensaio: 98%
• forma: solid
• índice de refração: n20/D 1.4763 (lit.)
• pb: 233 °C (lit.)
• pf: 33-36 °C (lit.)
• solubilidade: ethanol: soluble 5%, clear to slightly hazy, colorless to dark yellow
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: Cc1cc(nc(c1)C(C)(C)C)C(C)(C)C
• InChI: 1S/C14H23N/c1-10-8-11(13(2,3)4)15-12(9-10)14(5,6)7/h8-9H,1-7H3
• chave InChI: HVHZEKKZMFRULH-UHFFFAOYSA-N

Descrição

Descrição geral

2,6-Di-tert-butyl-4-methylpyridine is a sterically hindered, non-nucleophilic base which distinguishes between BrÖnsted (protonic) and Lewis acids. It also enables the direct high-yield conversion of aldehydes and ketones to vinyl triflates. It inhibits desilylation and hydration of the products during GaCl₃-catalyzed ortho-ethynylation of phenol.

Aplicação

2,6-Di-tert-butyl-4-methylpyridine has been used:

• in the synthesis of 1,2-dihydro-2-silanaphthalene derivatives
• as base in PtCl₄-catalyzed cyclization reactions of homopropargyl azide derivatives
• diastereoselective synthesis of β-thiomannopyranosides

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302,H315,H319,H335
• Declarações de precaução: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 183.2 °F - closed cup
• Ponto de fulgor (°C): 84 °C - closed cup
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves