All Photos(1)



Poly-L-ornithine solution

mol wt 30,000-70,000, 0.01%, sterile-filtered, BioReagent, suitable for cell culture

CAS Number:
MDL number:
PubChem Substance ID:

Quality Level



product line




mol wt



pkg of 50 mL




cell culture | mammalian: suitable


endotoxin, tested

shipped in


storage temp.


SMILES string


Related Categories

General description

Poly-L-ornithine is a positively charged synthetic amino acid polymer.


Poly-L-ornithine has been used successfully for the attachement and study of neural cell differentiation and outgrowth. Recommended as a cell culture substratum when using 0.5 ml of a 0.1 mg/ml solution to coat 25 cm2.
Poly-L-ornithine solution has been used in the induction of differentiation.

Biochem/physiol Actions

Poly-L-ornithine helps to improve the penetration of substances into cells. It can induce the uptake of DNA.

Preparation Note

Prepared in cell culture grade water.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

10 - Combustible liquids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Areechun Sotthibundhu et al.
EXCLI journal, 15, 829-841 (2017-03-10)
Melatonin, secreted mainly by the pineal gland, plays roles in various physiological functions including protecting cell death. We showed in previous study that the proliferation and differentiation of precursor cells from the adult mouse subventricular zone (SVZ) can be modulated...
Interferon (2009)
Plant Protoplasts: International Review of Cytology (2013)
Differential effect of activin on mouse embryonic stem cell differentiation in insulin?secreting cells under nestin?positive selection and spontaneous differentiation protocols.
Jafary H, et al.
Cell Biology International, 32(2), 278-286 (2008)
Ewoud B Compeer et al.
Nature communications, 9(1), 1597-1597 (2018-04-25)
Endocytosis of surface receptors and their polarized recycling back to the plasma membrane are central to many cellular processes, such as cell migration, cytokinesis, basolateral polarity of epithelial cells and T cell activation. Little is known about the mechanisms that...


Neural Stem Cell FAQs

Frequently asked questions about neural stem cells including NSC derivation, expansion and differentiation.

Derivation of Functional Oligodendrocyte Progenitor Cells (OPCs) from Human Neural Stem Cell Lines

Derivation and characterization of functional human neural stem cell derived oligodendrocyte progenitor cells (OPCs) that efficiently myelinate primary neurons in culture.

3D Cell Culture Tools and Techniques

3D cell culture overview. Learn about 2D vs 3D cell culture, advantages of 3D cell culture, and techniques available to develop 3D cell models

Cancer Stem Cells: Targets for Cancer Therapy

Cancer stem cell media, spheroid plates and cancer stem cell markers to culture and characterize CSC populations.

See All


Alzheimer’s In A Dish™: 3D Neural Stem Cell Models of Alzheimer's Disease

A stem cell culture protocol to generate 3D NSC models of Alzheimer’s disease using ReNcell human neural stem cell lines.

Neural Stem Cell Culture Protocols

Step-by-step culture protocols for neural stem cell culture including NSC isolation, expansion, differentiation and characterization.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service