Fibronectin is a ubiquitous protein of the extracellular matrix. It is a mosaic protein, that is made up of three types of repeating modular consensus amino acid sequences. Fibronectins belongs to a class of high-molecular-weight glycoproteins. Cellular fibronectin is expressed by fibroblasts and plasma fibronectin is usually liberated by hepatocytes.
Fibronectin (FN) bovine plasma has been used in:
- fibronectin and adsorption analysis (ELISA (enzyme-linked immunosorbent assay))
- transwell migration
- fibronectin assay
Fibronectins participate in cell adhesion, cytoskeletal organization, oncogenic transformation, cell migration, phagocytosis, hemostasis, and embryonic differentiation.
Protein homogeneity is evaluated by immunoelectrophoresis.
Product F1141, Fibronectin from bovine plasma is a solution in 0.05 M TBS pH 7.5.