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Tris(hydroxymethyl)aminomethane

TRIS LAB

Synonym(s):
Tris base, Trometamol, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM
Linear Formula:
NH2C(CH2OH)3
CAS Number:
Molecular Weight:
121.14
Beilstein:
741883
MDL number:
EC Index Number:
201-064-4

Quality Level

vapor pressure

0.0267 hPa ( 20 °C)

form

solid

potency

>5000 mg/kg LD50, oral (Rat)
>5000 mg/kg LD50, skin (Rat)

pH

10.2-10.6 (20 °C, 6 g/L in H2O)

useful pH range

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.)
219-220 °C/13.3 hPa

mp

167-172 °C (lit.)

solubility

678 g/L

density

1.35 g/cm3 at 23 °C

bulk density

840 kg/m3

storage temp.

15-25°C

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

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General description

TRIS LAB

Application

Tris(hydroxymethyl)aminomethane TRIS LAB. CAS 77-86-1, EC 201-064-4, chemical formula H₂NC(CH₂OH)₃.

Analysis Note

Assay (acidimetric, calc. on anhydrous substance)99.8 - 100.1 %Identity (IR-spectrum)conformsIn water insoluble matter≤ 0.005 %Absorbance (290 nm; 40 %; 1 cm; water)≤ 0.2Chloride (Cl)≤ 0.001 %Sulfate (SO₄)≤ 0.005 %Heavy metals (as Pb)≤ 0.0005 %Fe (Iron)≤ 0.0005 %Sulfated ash≤ 0.05 %Water (according to Karl Fischer)≤ 0.5 %

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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