RES3193T-A7

Tromethamine

• Synonym(s): Tromethamine, Tris
• Empirical Formula (Hill Notation): C₄H₁₁NO₃
• CAS Number: 77-86-1
• Molecular Weight: 121.14
• EC Number: 201-064-4
• MDL number: MFCD00004679
• PubChem Substance ID: 329824270
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: Endotoxin, microbial, and heavy metals; tested
• suitability: suitable for manufacturing use
• foreign activity: Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
• SMILES string: NC(CO)(CO)CO
• InChI: 1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
• InChI key: LENZDBCJOHFCAS-UHFFFAOYSA-N

Description

Application

Tromethamine is a commonly used biological buffer which is also referred to as Tris or Trizma. Tris as a buffer has very broad usage in diagnostics and downstream purifications. The pKa of Tris is 7.77 which corresponds closely to a physiological pH of 7.36.

Tromethamine is used in biopharmaceutical buffer formulations (both upstream and downstream), electrophoresis separations and diagnostic reagent formulations. Tromethamine is especially useful in downstream purification processes.

Packaging

Product is available in the following package sizes:
RES3193T-A701X: 100 gm container
RES3193T-A703X: 5 kg container
RES3193T-A705X: 25 kg container
RES3193T-A706X: 50 kg container

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable