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S1429

Sigma-Aldrich

Sodium acetate

meets USP testing specifications, anhydrous

Synonym(s):
Acetic acid sodium salt
Linear Formula:
CH3COONa
CAS Number:
Molecular Weight:
82.03
Beilstein:
3595639
EC Number:
MDL number:
eCl@ss:
39021906
PubChem Substance ID:
NACRES:
NA.21

Quality Level

grade

anhydrous

agency

USP/NF
meets USP testing specifications

assay

99-101% dry basis

form

solid

autoignition temp.

1112 °F

pH

8.5-9.9 (25 °C, 246 g/L)

pKa 

4.76 (acetic acid)

mp

>300 °C (dec.) (lit.)

solubility

soluble 246 g/L at 20 °C (completely)

application(s)

pharmaceutical (small molecule)

SMILES string

[Na+].CC([O-])=O

InChI

1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

InChI key

VMHLLURERBWHNL-UHFFFAOYSA-M

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General description

Sodium acetate (SA) exhibits antimicrobial and antioxidant properties. It is used as an exchange-fluid buffer in hemodialysis. SA acts as an a alkalinizing agent and its continuous intravenous (IV) infusion causes salicylate intoxication.

Application

Sodium acetate (SA) has been used to increase hepatic acetyl- coenzyme A in caloric restricted rats.

Packaging

100 g in poly bottle
1 kg in poly bottle

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

Mechanisms by which a very-low-calorie diet reverses hyperglycemia in a rat model of type 2 diabetes
Perry RJ, et al.
Cell Metabolism, 27(1), 210-217 (2018)
Enhancement of in-vitro human interleukin-1 production by sodium acetate
Bingel M, et al.
Lancet, 329(8523), 14-16 (1987)
Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon
Sallam KI, et al.
Food Control, 18(5), 566-575 (2007)
Sodium Acetate as an Alkalinizing Agent for Salicylate Intoxication: A Case Report
Groke SF, et al.
Journal of Clinical Toxicology (2015)
Amanda P De Souza et al.
Journal of experimental botany, 66(14), 4351-4365 (2015-04-25)
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