PHR1446

Ramipril

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonim(y): Tritace, [2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
• Wzór empiryczny (zapis Hilla): C₂₃H₃₂N₂O₅
• Numer CAS: 87333-19-5
• Masa cząsteczkowa: 416.51
• Numer MDL: MFCD00865775
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329822606
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material; pharmaceutical secondary standard
• Poziom jakości: 300
• agency: traceable to BP 751; traceable to Ph. Eur. R0145000; traceable to USP 1598303
• rodzina API: ramipril
• Certyfikat analizy: current certificate can be downloaded
• opakowanie: pkg of 1 g
• metody: HPLC: suitable; gas chromatography (GC): suitable
• Zastosowanie: pharmaceutical (small molecule)
• Format: neat
• temp. przechowywania: 2-8°C
• ciąg SMILES: O=C(N1[C@](CCC2)([H])[C@]2([H])C[C@H]1C(O)=O)[C@H](C)N[C@H](C(OCC)=O)CCC3=CC=CC=C3
• InChI: 1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
• Klucz InChI: HDACQVRGBOVJII-JBDAPHQKSA-N
• informacje o genach: human ... ACE(1636)

Opis

Opis ogólny

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Ramipril is an angiotensin-converting-enzyme (ACE) inhibitor, which acts on the renin angiotensin aldosterone system. It is widely used in reducing hypertension by the suppression of the effects of angiotensin II at its receptor, thereby blocking the renin-angiotensin system.

Zastosowanie

Ramipril may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique and high-performance liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Działania biochem./fizjol.

Angiotensin converting enzyme (ACE) inhibitor.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAC3757 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H360FD
• Zwroty wskazujące środki ostrożności: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Klasyfikacja zagrożeń: Repr. 1B
• Kod klasy składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable