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900400P
Avanti
Palmitic acid (15-yne)
Avanti Research™ - A Croda Brand 900400P, powder
Synonim(y):
15-hexadecynoic acid
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About This Item
Wzór empiryczny (zapis Hilla):
C16H28O2
Numer CAS:
Masa cząsteczkowa:
252.39
Kod UNSPSC:
12352211
NACRES:
NA.25
Polecane produkty
Formularz
powder
opakowanie
pkg of 1 × 1 mg (900400P-1mg)
pkg of 1 × 5 mg (900400P-5mg)
producent / nazwa handlowa
Avanti Research™ - A Croda Brand 900400P
typ lipidu
click reagents
Warunki transportu
dry ice
temp. przechowywania
−20°C
ciąg SMILES
OC(CCCCCCCCCCCCCC#C)=O
InChI
1S/C16H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h1H,3-15H2,(H,17,18)
Klucz InChI
PUZGUNYANHPRKM-UHFFFAOYSA-N
Zastosowanie
Palmitic acid (15-yne) has been used as a component of fatty acid probe stock solution for the optimization of Alk-C16 incorporation onto cellular proteins. It is also suitable for metabolic labeling.
Działania biochem./fizjol.
Alkynyl palmitic acid (aPA) is a modified palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry′. The click chemistry reactions are rapid, convenient, versatile and regiospecific. They are easy to purify. aPA can be used for isolating palmitoylated proteins.
Opakowanie
5 mL Amber Glass Screw Cap Vial (900400P-1mg)
5 mL Amber Glass Screw Cap Vial (900400P-5mg)
Informacje prawne
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
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Certyfikaty analizy (CoA)
Lot/Batch Number
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Christopher D Hein et al.
Pharmaceutical research, 25(10), 2216-2230 (2008-05-30)
Click chemistry refers to a group of reactions that are fast, simple to use, easy to purify, versatile, regiospecific, and give high product yields. While there are a number of reactions that fulfill the criteria, the Huisgen 1,3-dipolar cycloaddition of
Stephen B Milne et al.
Nature chemical biology, 6(3), 205-207 (2010-01-26)
Alkyne-modified phospholipids can be unambiguously identified and differentiated from native species in complex mixtures by formation of dicobalthexacarbonyl complexes. This reaction is specific for alkynes and is unaffected by other glycerophospholipid-related moieties. Enrichment of cells with alkyne-derivatized fatty acids or
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FEBS letters, 585(15), 2501-2506 (2011-07-12)
Palmitoylation of the Wnt and Hedgehog proteins is critical for maintaining their physiological functions. To date, there are no reported studies that characterize the cellular distribution of the palmitoylated forms of these proteins. Here, we describe the subcellular localization of
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Progress in understanding the biology of protein fatty acylation has been impeded by the lack of rapid direct detection and identification methods. We first report that a synthetic omega-alkynyl-palmitate analog can be readily and specifically incorporated into GAPDH or mitochondrial
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