QBD10512

Azido-dPEG^®₈-acid

• Synonim(y): Polyethylene glycol
• Wzór empiryczny (zapis Hilla): C₁₉H₃₇N₃O₁₀
• Numer CAS: 1214319-92-2
• Masa cząsteczkowa: 467.51
• Numer MDL: MFCD21363300
• Kod UNSPSC: 12352106
• Identyfikator substancji w PubChem: 329823934
• NACRES: NA.22

Właściwości

• Próba: >90%
• Postać: solid or viscous liquid
• przydatność reakcji: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• grupa funkcyjna: azide; carboxylic acid
• architektura polimerowa: shape: linear; functionality: heterobifunctional
• Warunki transportu: ambient
• temp. przechowywania: −20°C
• ciąg SMILES: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

Opis

Cechy i korzyści

The azido-dPEG^®₈ contains an azide function on one end of a single molecular weight dPEG^® spacer (32.2Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Informacje prawne

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable