933910

Linear polyethylenimine-block-poly(ethylene glycol)

PEG average M_n 5,000, PEI average M_n 30,000

• Synonim(y): PEG-b-PEI, Poly(ethylene glycol)-block-polyethylenimine
• Wzór liniowy: CH₃(C₂H₄O)_n(C₂H₅N)_mOH
• Kod UNSPSC: 12352207
• NACRES: NA.21

Właściwości

• Postać: powder or solid
• Poziom jakości: 100
• masa cząsteczkowa: PEG 5,000 Da; PEG average M_n 5,000; PEI 30,000 Da; PEI average M_n 30,000
• kolor: white to pale yellow
• temp. przechowywania: 2-8°C

Opis

Zastosowanie

Due to their low immunogenicity profiles, polymeric nonviral vectors have shown promise in advancing the treatment of many severe genetic and acquired diseases via gene therapy.
Poly(ethyleneimine) is one of the most commonly used cationic polymers for gene delivery applications. Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable