SML1595

Luliconazole

≥98% (HPLC)

• 別名: (αE)-α-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile, NND 502, [R-(E)]-α-[4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile
• 実験式（ヒル表記法）: C₁₄H₉Cl₂N₃S₂
• CAS番号: 187164-19-8
• 分子量: 354.28
• MDL番号: MFCD00953915
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825485
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 20 mg/mL, clear
• 保管温度: −20°C
• SMILES記法: N#C/C(N1C=NC=C1)=C2SC[C@@H](C3=C(Cl)C=C(Cl)C=C3)S/2
• InChI: 1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
• InChI Key: YTAOBBFIOAEMLL-REQDGWNSSA-N

詳細

詳細

Luliconazole also called LLCZ, {(−)-(E)-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl) acetonitrile} is optically active compound. It is used as a topical medicine for treating dermatophytosis and dermatitis. It is a potential antifungal against Candida and other fungal infections of skin, groin and feet.

生物化学的／生理学的作用

Luliconazole is an imidazole antifungal. Its mechanism of action involves inhibition of ergosterol biosynthesis by inhibition of sterol 14α-demethylase.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319
• 注意書き: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable