SML0334

DMPQ dihydrochloride

≥98% (HPLC)

• 別名: 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride
• 実験式（ヒル表記法）: C₁₆H₁₄N₂O₂ · 2HCl
• CAS番号: 1123491-15-5
• 分子量: 339.22
• MDL番号: MFCD02262123
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825339
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: H₂O: >10 mg/mL
• 保管温度: room temp
• SMILES記法: Cl.Cl.COc1cc(OC)c2cc(cnc2c1)-c3ccncc3
• InChI: 1S/C16H14N2O2.2ClH/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11;;/h3-10H,1-2H3;2*1H
• InChI Key: YBBAOKYVJCNJIV-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

DMPQ is a potent selective inhibitor of human vascular beta-type platelet derived growth factor receptor tyrosine kinase (PDGFR?) with IC₅₀ = 80 nM. It is > 100-fold selective over EGFR, erbB2, p56, protein kinase A and protein kinase C.

特徴および利点

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable