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品質水準
アッセイ
≥98% (HPLC)
フォーム
powder
アプリケーション
metabolomics
vitamins, nutraceuticals, and natural products
保管温度
2-8°C
SMILES記法
Cl.COc1ccc2c(c1)[nH]c3c(C)nccc23
InChI
1S/C13H12N2O.ClH/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13;/h3-7,15H,1-2H3;1H
InChI Key
VNPLYCKZIUTKJM-UHFFFAOYSA-N
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詳細
Harmine hydrochloride is an alkaloid found in Peganum harmala.
生物化学的/生理学的作用
CNS stimulant.
Harmine hydrochloride has been considered for treatment of cancer and cerebral diseases and is a known CNS stimulant.
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral - Carc. 2
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SMB00461-VAR:
SMB00461-100MG:
SMB00461-BULK:
最新バージョンのいずれかを選択してください:
Stephanie F Bellmaine et al.
eLife, 6 (2017-09-09)
Genetic analysis has revealed that the dual specificity protein kinase DYRK1A has multiple roles in the development of the central nervous system. Increased DYRK1A gene dosage, such as occurs in Down syndrome, is known to affect neural progenitor cell differentiation
Xiuyun Li et al.
Frontiers in microbiology, 10, 2295-2295 (2019-11-22)
Several studies have demonstrated the significant antiviral, antimicrobial, antiplasmodial, antioxidative, antifungal, antimutagenic, and antitumor properties of harmine hydrochloride (HMH). The main objective of the present study was to investigate the antifungal effects and underlying mechanisms of HMH when combined with
Michael Tarpley et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 162, 105821-105821 (2021-03-31)
DYRK1A (dual-specificity tyrosine phosphorylation-regulated kinase 1a) is highly expressed in glioma, an aggressive brain tumor, and has been proposed as a therapeutic target for cancer. In the current study, we have used an optimized and validated time-resolved fluorescence energy transfer
Elisangela G Cata-Preta et al.
Frontiers in pharmacology, 9, 561-561 (2018-06-14)
Ayahuasca is a hallucinogenic beverage produced from the decoction of Banisteriopsis caapi (Bc) and Psychotria viridis (Pv), β-carboline- and N,N-dimethyltryptamine(DMT)-containing plants, respectively. Accumulating evidence suggests that ayahuasca may have therapeutic effects on ethanol abuse. It is not known, however, whether
Marlaina R Stocco et al.
Molecular neurobiology, 57(11), 4608-4621 (2020-08-08)
CYP2D6 metabolically inactivates several neurotoxins, including beta-carbolines, which are implicated in neurodegenerative diseases. Variation in CYP2D6 within the brain may alter local inactivation of neurotoxic beta-carbolines, thereby influencing neurotoxicity. The beta-carboline harmine, which induces hypothermia and tremor, is metabolized by
Global Trade Item Number
カタログ番号 | GTIN |
---|---|
SMB00461-100MG | 4061833052501 |
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