H3023

20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid

≥90% (HPLC), liquid, Ras/MAP pathway activitor

• 別名: 20-HETE, 20-Hydroxyarachidonic acid
• 実験式（ヒル表記法）: C₂₀H₃₂O₃
• CAS番号: 79551-86-3
• 分子量: 320.47
• MDL番号: MFCD00171542
• UNSPSCコード: 12352106
• PubChem Substance ID: 24895546
• NACRES: NA.77

特性

• product name: 20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid, ~100 μg/mL in ethanol, ≥90% (HPLC)
• アッセイ: ≥90% (HPLC)
• 形状: liquid
• 濃度: ~100 μg/mL in ethanol
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: OCCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
• InChI: 1S/C20H32O3/c21-19-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(22)23/h1,3-4,6-7,9-10,12,21H,2,5,8,11,13-19H2,(H,22,23)/b3-1-,6-4-,9-7-,12-10-
• InChI Key: NNDIXBJHNLFJJP-DTLRTWKJSA-N

詳細

生物化学的／生理学的作用

20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid (20-HETE) is an arachidonic acid metabolite via cytochrome P4504A, that is an activator of the Ras/MAP (microtubule-associated protein) pathway. 20-HETE acid is a predominant arachidonic acid present in the kidney. It is involved in the regulation of sodium, potassium and chloride transport in the renal tubules. 20-HETE is often excreted in urine in the form of glucuronide conjugate and sometimes as free acids. Increased urine 20-HETE is observed during pregnancy in rats.

包装

アルゴン封入包装。

安全性情報

• ピクトグラム: GHS02,GHS07
• シグナルワード: Danger
• 危険有害性情報: H225,H319
• 注意書き: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Flam. Liq. 2
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 57.2 °F - closed cup
• 引火点(℃): 14.0 °C - closed cup
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)