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Merck

PHR1767

Supelco

メラトニン

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

N-アセチル-5-メトキシトリプタミン

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About This Item

実験式(ヒル表記法):
C13H16N2O2
CAS番号:
分子量:
232.28
Beilstein:
205542
EC Number:
MDL番号:
UNSPSCコード:
41116107
PubChem Substance ID:
NACRES:
NA.24

グレード

certified reference material
pharmaceutical secondary standard

品質水準

認証

traceable to BP 1077
traceable to USP 1380105

APIファミリー

melatonin

形状

solid

CofA

current certificate can be downloaded

包装

pkg of 500 mg

テクニック

HPLC: suitable
gas chromatography (GC): suitable

mp

116.5-118 °C (lit.)

アプリケーション

pharmaceutical (small molecule)

保管温度

2-8°C

SMILES記法

COc1ccc2[nH]cc(CCNC(C)=O)c2c1

InChI

1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)

InChI Key

DRLFMBDRBRZALE-UHFFFAOYSA-N

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詳細

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. It is analyzed using GMP validated instruments as per pharmacopeia monograph methods and is traceable to Unites States Pharmacopeia (USP), European Pharmacopeia (EP), and British Pharmacopeia (BP) primary standards, wherever applicable. It is provided with a comprehensive certificate of analysis (CoA) containing a certified purity value, calculated by the mass balance approach.
All information regarding the use of this CRM can be found on the certificate of analysis.

Melatonin is a methoxyindole compound secreted by the pineal gland in the mammalian brain. It regulates the sleep-wake cycles (circadian rhythm) and also has anti-inflammatory and antioxidant properties.

アプリケーション

Melatonin pharmaceutical reference standard may also be used as follows:
  • Development and validation of a high-performance liquid chromatography (HPLC) method combined with UV detection to determine melatonin in capsule dosage forms
  • Determination of melatonin in dog plasma samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS) method
  • Simultaneous electrochemical analysis of melatonin and 5-hydroxytryptophan by poly-(melamine)/poly-(o-aminophenol) modified screen printed electrodes (SPCs) in human urine samples
  • Determination of melatonin in pharmaceutical formulations by voltammetric and amperometric methods using carbon black modified glassy carbon electrode
  • Electroanalytical determination of melatonin in tablet and human urine samples using a boron-doped diamond electrode and square-wave voltammetry (SWV)
  • Development of nanopalladium polymeric nanocomposite modified glassy carbon electrode (GCE) for qualitative and quantitative analyses of melatonin in tablets and human urine samples by square-wave voltammetry
  • Liquid chromatography-diode array detection (LC-DAD) of melatonin dose in supplements and also detection of impurities present in supplements by ultra-high-performance liquid chromatography-orbitrap mass spectrometry (UHPLC-orbitrap-MS)

その他情報

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

脚注

To see an example of a Certificate of Analysis for this material enter LRAA8251 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

保管分類コード

11 - Combustible Solids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

PHR1767-500MG:
PHR1767-BULK:
PHR1767-500MG-PW:
PHR1767-1G-PW:


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試験成績書(COA)

Lot/Batch Number

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