164598

Aminopeptidase M, Porcine Kidney

• 別名: Aminopeptidase M, Porcine Kidney, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N
• CAS番号: 9054-63-1
• Enzyme Commission number: 3.4.11.2 (BRENDA, IUBMB)
• MDL番号: MFCD00131501
• UNSPSCコード: 12352202
• NACRES: NA.54

特性

• 由来生物: Porcine kidney
• 品質水準: 100
• フォーム: suspension (crystalline)
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white
• 溶解性: physiological buffer: soluble; water: soluble
• その他の活性: Oxidases ≤3%
• 輸送温度: ambient
• 保管温度: 2-8°C

詳細

詳細

Aminopeptidase M (APM) is abundantly found in brush border membranes of the kidney, small intestine, placenta, and liver. It is a type II integral membrane protein, known as ectoenzyme.

アプリケーション

Aminopeptidase M, porcine kidney has been used:

• to test and identify the peaks containing d-residue in the allatotropin-related peptide (ATRP)
• to study its oxidative inactivation of enzyme activity, and to screen MIRA ingredients
• for the proteolysis of isolevuglandins (IsoLGs) proteins

生物化学的／生理学的作用

Aminopeptidase M (APM) is implicated in terminating the actions of certain neuropeptides, like the enkephalins and angiotensin III in the brain. It also metabolizes specific vasoactive peptides. It functions as a receptor for certain viruses, such as coronavirus 229E. APM is a nonspecific peptidase, which rapidly breaks down l-residue peptides.

包装

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Harmful (C)

単位の定義

One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of Leu-pNA per min at 37°C, pH 7.2.

物理的形状

Crystalline suspension in 3.2 M (NH₄)₂SO₄, 10 mM MgCl₂, 10 mM Tris-HCl, pH 7.5.

その他情報

Wachsmuth, E.E., et al. 1966. Biochemistry5, 169.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable