A-003

6-Acetylmorphine, 100 μg/mL solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• 別名: 6-Acetylmorphine solution
• 実験式（ヒル表記法）: C₁₉H₂₁NO₄
• CAS番号: 2784-73-8
• 分子量: 327.37
• EC Number: 200-835-2
• MDL番号: MFCD00467140
• UNSPSCコード: 41116107
• PubChem Substance ID: 329770565
• NACRES: NA.24

特性

• グレード: certified reference material
• 品質水準: 300
• フォーム: liquid
• 特徴: SNAP-N-SPIKE^®. SNAP-N-SHOOT^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 100 μg/mL in acetonitrile
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: forensics and toxicology
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35
• InChI: 1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1
• InChI Key: JJGYGPZNTOPXGV-SSTWWWIQSA-N

詳細

詳細

6-Acetylmorphine, also known as 6-monoacetylmorphine or 6-MAM, is an active metabolite of heroin and biomarker for heroin usage. This Certified Spiking Solution^® is suitable for use as a starting material in calibrators and controls for GC/MS or LC/MS methods in forensic analysis, clinical toxicology, urine drug testing, or pain prescription monitoring.

アプリケーション

• Drug use monitoring: The utility of 6-acetylmorphine as a specific biomarker in workplace drug testing for identifying illicit heroin use among morphine-positive urine specimens was highlighted, affirming its importance in forensic and clinical toxicology (Vikingsson et al., 2024).


• Physiological monitoring technology: The detection of 6-acetylmorphine in sweat at the molecular level demonstrates the potential of the wearable SERS sensor in monitoring drug use (Liu et al., 2024).


• Drug effect attenuation research: A bivalent conjugate vaccine inducing dual immunogenic responses was studied to attenuate the effects of heroin and fentanyl in mice, utilizing 6-acetylmorphine as a component, demonstrating its potential in therapeutic developments (Barrientos et al., 2021).


• Behavioral toxicology: The determination of drugs of abuse in hair samples using LC-MS/MS, which included 6-acetylmorphine, provided vital data for investigations related to suicide attempts, highlighting its utility in clinical and forensic toxicology (Cardoso et al., 2022).

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS07
• シグナルワード: Danger
• 危険有害性情報: H225,H302 + H312 + H332,H319
• 注意書き: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 2
• 引火点(°F): 35.6 °F - closed cup
• 引火点(℃): 2 °C - closed cup