900915

N-Azidoacetylgalactosamine-tetraacylated

• 別名: Ac₄GalNAz
• 実験式（ヒル表記法）: C₁₆H₂₂N₄O₁₀
• CAS番号: 653600-56-7
• 分子量: 430.37
• MDL番号: MFCD26961128
• UNSPSCコード: 12352116
• NACRES: NA.22

特性

• フォーム: powder or crystals
• 品質水準: 100
• 反応適合性: reaction type: click chemistry
• 保管温度: −20°C
• SMILES記法: [N+](=[N-])=NCC(=O)NC1[C@@H](OC([C@@H](C1OC(=O)C)OC(=O)C)COC(=O)C)OC(=O)C
• InChI: 1S/C16H22N4O10/c1-7(21)26-6-11-14(27-8(2)22)15(28-9(3)23)13(16(30-11)29-10(4)24)19-12(25)5-18-20-17/h11,13-16H,5-6H2,1-4H3,(H,19,25)/t11?,13?,14-,15?,16+/m0/s1
• InChI Key: HGMISDAXLUIXKM-SROHTVIFSA-N

詳細

アプリケーション

N-Azidoacetylgalactosamine-tetraacylated (Ac₄GalNAz) provides the first part of a simple and robust two-step technique that helps identify and characterize cell surface sialic acid-containing glycoproteins. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable