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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Sinonimi:
EPND, GluN2A, NMDAR2A, NR2A
Specie:
ID UniProtKB:
ID gene:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
1,4-bis(3-aminopropil)piperazina, ≥99%,
Specie
rat
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Specie
human
Dextromethorphan hydrobromide, meets USP testing specifications,
Specie
human

Small Molecule - Allosteric Modulator

N° Catalogo
Descrizione
Specie
4-Aminopiperidine, ,
Specie
rat
Kainic acid monohydrate, ≥99% (TLC),
Specie
human, mouse, rat
Acamprosate calcium, ≥98% (HPLC), powder,
Specie
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Specie
human
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Glicina, ReagentPlus®, ≥99% (HPLC),
Specie
rat
Glicina, suitable for electrophoresis, ≥99%,
Specie
rat
Glicina, BioUltra, for molecular biology, ≥99.0% (NT),
Specie
rat
Glicina, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
Specie
rat
Glicina, ,
Specie
rat

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-NR2A Antibody, clone A12W, rabbit monoclonal, culture supernatant, clone A12W, Upstate®,
Reattività con
mouse, rat
Applicazione
western blot
Anticorpo anti-NR2A, Upstate®, from rabbit,
Reattività con
mouse, rat
Applicazione
immunoprecipitation (IP)
western blot
Anti-NMDAR2A Antibody, Chemicon®, from rabbit,
Reattività con
fish, human, mouse, rat
Applicazione
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-phospho NMDAR2A (Ser1459), ,
Reattività con
human
Applicazione
immunocytochemistry
western blot
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327-95, purified immunoglobulin,
Reattività con
human, mouse, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Specie
human
Agmatine sulfate salt, ≥97%, powder,
Specie
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Specie
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Indole-2-carboxylic acid, 98%,
Specie
rat, human
1,3-Diphenylguanidine, 97%,
Specie
rat, mouse, human
Quisqualic acid, powder,
Specie
rat
Nω-Nitro-L-arginine, ≥98% (TLC),
Specie
rat, mouse, human
Pentamidine isethionate salt, powder,
Specie
human

Small Molecule - Mixed Agonist/Antagonist

N° Catalogo
Descrizione
Specie
1,3-Diaminopropane, ≥99%,
Specie
rat
N,N′-Dimethyl-1,3-propanediamine, 97%,
Specie
rat
N,N,N′,N′-Tetramethyl-1,3-propanediamine, ≥99%,
Specie
rat
1,3-Diamino-2-propanol, 95%,
Specie
rat
N-Methyl-1,3-diaminopropane, 98%,
Specie
rat

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human GRIN2A,
Specie
human
MISSION® esiRNA, targeting mouse Grin2a,
Specie
mouse