G5417

Glicina

• Sinonimo/i: Acido aminoacetico, Acido aminoetanoico, Glicocolla
• Formula condensata: NH₂CH₂COOH
• Numero CAS: 56-40-6
• Peso molecolare: 75.07
• Beilstein: 635782
• Numero CE: 200-272-2
• Numero MDL: MFCD00008131
• Codice UNSPSC: 12352209
• eCl@ss: 32160406
• NACRES: NA.25

Proprietà

• Origine biologica: non-animal source
• Livello qualitativo: 400
• Saggio: ≥98.5%
• Forma fisica: crystalline powder
• tecniche: cell culture | mammalian: suitable
• Impurezze: endotoxin, heavy metals, trace metals, residual solvents, tested
• pH: 5.9-6.4
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• Punto di fusione: 240 °C (dec.) (lit.)
• Solubilità: H₂O: 100 mg/mL
• Assorbanza UV: λ: 260 nm A_max: ≤0.04; λ: 260 nm A_max: -0.006; λ: 280 nm A_max: ≤0.04; λ: 280 nm A_max: -0.003
• Compatibilità: suitable for manufacturing use
• applicazioni: pharmaceutical (small molecule)
• Attività estranea: cytotoxicity, tested
• Stringa SMILE: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5); DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Informazioni sul gene: rat ... Grin2a(24409)

Descrizione

Descrizione generale

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

To request the documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Applicazioni

Glycine is a non-essential amino acid. It is the simplest of the amino acids and plays various roles in biology. It is structurally unique among the biological amino acids in that it does not have an asymmetric center, and thus is not chiral. It is commonly used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Azioni biochim/fisiol

Neurotrasmettitore inibitore nella colonna vertebrale, regolatore allosterico di recettori NMDA.

Note legali

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)