PHR1527

Dexamethasone Acetate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinonimo/i: Dexamethasone 21-acetate, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate
• Formula empirica (notazione di Hill): C₂₄H₃₁FO₆
• Numero CAS: 1177-87-3
• Peso molecolare: 434.50
• Beilstein: 2342608
• Numero CE: 214-646-8
• Numero MDL: MFCD00027407
• Codice UNSPSC: 41116107
• ID PubChem: 329823439
• NACRES: NA.24

Proprietà

• Origine biologica: synthetic
• Livello qualitativo: 300
• Grado: certified reference material; pharmaceutical secondary standard
• agenzia: BP; EP; USP; traceable to Ph. Eur. D0710000; traceable to USP 1176506
• Tensione di vapore: <0.0000001 kPa ( 25 °C)
• Famiglia di API: dexamethasone
• CdA: current certificate can be downloaded
• Confezionamento: pkg of 1 g
• Condizioni di stoccaggio: protect from light (20 mm aluminium crimp seal for unused portion)
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• Colore: white
• Punto di fusione: 460.4-464 °F (238—240°C)
• Solubilità: acetone: freely soluble; dichloromethane: slightly soluble; methanol: freely soluble; water: practically insoluble
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Condizioni di spedizione: ambient
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1; AKUJBENLRBOFTD-RPRRAYFGSA-N
• Informazioni sul gene: human ... NR3C1(2908)

Descrizione

Descrizione generale

Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Dexamethasone Acetate is a steroid used for the treatment of various diseases because of its anti-inflammatory and inmunosuppresor effects. It is a common component of ointments, creams, lotions, aerosols and microemulsions.

Applicazioni

Dexamethasone Acetate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

Dexamethasone acetate is used as a pharmaceutical reference standard for the quantification the analyte in pharmaceutical formulations using liquid chromatography (LC) technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAA3645 in the slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H360FD
• Consigli di prudenza: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classi di pericolo: Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable