1176007

Desametasone

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: (11β,16α)-9-fluoro-11,17,21-triidrossi-16-metilpregna-1,4-diene-3,20-dione, 9α-fluoro-16α-metil-11β,17α,21-triidrossi-1,4-pregnadiene-3,20-dione, 9α-fluoro-16α-metilprednisolone, Prednisolone F
• Formula empirica (notazione di Hill): C₂₂H₂₉FO₅
• Numero CAS: 50-02-2
• Peso molecolare: 392.46
• Beilstein: 2066651
• Numero MDL: MFCD00064136
• Codice UNSPSC: 41116107
• ID PubChem: 329749548
• NACRES: NA.24

Proprietà

• Origine biologica: synthetic
• Grado: pharmaceutical primary standard
• agenzia: USP
• Tensione di vapore: <0.0000001 kPa ( 25 °C)
• Famiglia di API: dexamethasone
• Confezionamento: pkg of 125 mg
• Produttore/marchio commerciale: USP
• Colore: white
• Punto di fusione: 262-264 °C (lit.)
• Solubilità: acetone: sparingly soluble; chloroform: slightly soluble; ethanol: sparingly soluble; ether: very slightly soluble; methanol: sparingly soluble; water: practically insoluble
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1; UREBDLICKHMUKA-CXSFZGCWSA-N
• Informazioni sul gene: human ... NR3C1(2908)

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Dexamethasone Related Compound J USP reference standard for use in specified quality tests and assays.

Also used to prepare system suitability and standard solution during the performance test and impurity analysis by using liquid chromatography in conjunction with UV detector according to the given below monographs of United States Pharmacopeia (USP) :

• Dexamethasone.
• Dexamethasone Tablets.
• Dexamethasone Oral Solution.
• Dexamethasone Sodium Phosphate Ophthalmic Solution.

Dexamethasone USP reference standard may be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations, and biological samples by various analytical techniques.

Azioni biochim/fisiol

Agente antinfiammatorio glucocorticoide. Regola la sopravvivenza, la crescita e la differenziazione delle cellule T. Inibisce l′induzione dell′ossido nitrico sintasi.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H360FD
• Consigli di prudenza: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classi di pericolo: Repr. 1B
• Codice della classe di stoccaggio: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable