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Key Documents

76526

Supelco

L-Leucine

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Sinonimo/i:

(S)-2-Amino-4-methylpentanoic acid

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About This Item

Formula condensata:
(CH3)2CHCH2CH(NH2)CO2H
Numero CAS:
Peso molecolare:
131.17
Beilstein:
1721722
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
eCl@ss:
32160406
ID PubChem:
Numero E:
E641
NACRES:
NA.24

Grado

certified reference material
TraceCERT®

Livello qualitativo

Nome Commerciale

TraceCERT®

Classi chimiche degli analiti

amino acids, peptides, proteins

Produttore/marchio commerciale

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Colore

white

Punto di fusione

>300 °C (lit.)

applicazioni

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

Formato

neat

Temperatura di conservazione

20-25°C

Stringa SMILE

CC(C)C[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
ROHFNLRQFUQHCH-YFKPBYRVSA-N

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Descrizione generale

L-Leucine is an important and essential branched chain amino acid. It shows activity with the mechanistic target of rapamycin(mTOR) pathway, involved in the synthesis of proteins and satiety.
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Check out the entire portfolio of our amino acids certified reference materials (CRM)

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Note legali

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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Fleck M and Petrosyan.MA et al.
Salts of Amino Acids: Crystallization, Structure and Properties (2014)
Mullin.EG, et al. et al.
Integrative Weight Management: A Guide for Clinicians (2014)
William I A Haynes et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(11), 4804-4814 (2013-03-15)
The identification of a hyperdirect cortico-subthalamic nucleus connection highlighted the important role of the subthalamic nucleus (STN) in regulating behavior. However, this pathway was shown primarily from motor areas. Hyperdirect pathways associated with cognitive and motivational cortical regions are particularly
Qian Wang et al.
Journal of the National Cancer Institute, 105(19), 1463-1473 (2013-09-21)
L-type amino acid transporters (LATs) uptake neutral amino acids including L-leucine into cells, stimulating mammalian target of rapamycin complex 1 signaling and protein synthesis. LAT1 and LAT3 are overexpressed at different stages of prostate cancer, and they are responsible for
T Yoshimasa et al.
The Journal of clinical investigation, 69(3), 643-650 (1982-03-01)
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with

Protocolli

Separation of L-Alanine; Glycine; L-Valine; L-Leucine; L-Isoleucine; L-Proline; L-Methionine; L-Serine; L-Threonine; L-Phenylalanine; L-Aspartic acid; L-4-Hydroxyproline; L-Cysteine; L-Glutamic acid; L-Asparagine; L-Lysine; L-Glutamine; L-Histidine; L-Tyrosine; L-Tryptophan; L-Cystine

Chromatograms

application for HPLC

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