L8000

L-Leucine

≥98% (HPLC), suitable for ligand binding assays

• Sinonimo/i: (S)-2-Amino-4-methylpentanoic acid
• Formula condensata: (CH₃)₂CHCH₂CH(NH₂)CO₂H
• Numero CAS: 61-90-5
• Peso molecolare: 131.17
• Beilstein: 1721722
• Numero CE: 200-522-0
• Numero MDL: MFCD00002617
• Codice UNSPSC: 12352209
• eCl@ss: 32160406
• ID PubChem: 24896488
• NACRES: NA.26

Proprietà

• Nome del prodotto: L-Leucine, reagent grade, ≥98% (HPLC)
• Grado: reagent grade
• Livello qualitativo: 200
• Saggio: ≥98% (HPLC)
• Stato: powder
• tecniche: ligand binding assay: suitable
• Impurezze: isoleucine and methionine, essentially free
• Colore: white to off-white
• Punto di fusione: >300 °C (lit.)
• applicazioni: peptide synthesis
• Stringa SMILE: CC(C)C[C@H](N)C(O)=O
• InChI: 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1; ROHFNLRQFUQHCH-YFKPBYRVSA-N

Descrizione

Applicazioni

L-Leucine has been used as an agonist of mechanistic target of rapamycin (mTOR) to determine whether AMPK/mTOR pathway is involved in berberine-mediated autophagy in J774A.1 cells. It has also been used for the selection of transformed cells.

Azioni biochim/fisiol

Leucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)