850345P

14:0 PC (DMPC)

1,2-dimyristoyl-sn-glycero-3-phosphocholine, powder

• Sinonimo/i: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine; DMPC; PC(14:0/14:0)
• Formula empirica (notazione di Hill): C₃₆H₇₂NO₈P
• Numero CAS: 18194-24-6
• Peso molecolare: 677.93
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Saggio: >99% (TLC)
• Forma fisica: powder
• Confezionamento: pkg of 1 × 1 g (850345P-1g); pkg of 1 × 200 mg (850345P-200mg); pkg of 1 × 25 mg (850345P-25mg); pkg of 1 × 500 mg (850345P-500mg)
• Produttore/marchio commerciale: Avanti Polar Lipids 850345P
• Tipo di lipide: phospholipids; cardiolipins
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O
• InChI: 1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m0/s1; CITHEXJVPOWHKC-UMSFTDKQSA-N

Descrizione

Descrizione generale

Dimyristoylphosphatidylcholine (DMPC) belongs to the phosphatidylcholine (PCs) family. It is composed of saturated and symmetric phospholipids with 14 carbon atoms. DMPC is zwitterionic glycerophospholipid and is associated with mammalian membranes.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Applicazioni

14:0 PC (DMPC) has been used:

• in the preparation of liposomes for dissipation monitoring and perforin binding and assembly by Quartz crystal microscopy studies.
• in anthraquinone liposomes generation for spectral studies
• in bicelles preparation along with phosphatidylinositol 4,5-bisphosphate for in vitro reconstitution of β2-adrenergic receptor

Azioni biochim/fisiol

Dimyristoylphosphatidylcholine (DMPC) in combination with cholesterol is used as biomembrane model. Oral supplementation of DMPC in apolipoprotein (apo) E−null mice, improves high density lipoprotein levels and other lipid profiles, preventing the pathogenesis of atherosclerosis.

Confezionamento

20 mL Clear Glass Screw Cap Vial (850345P-1g)

20 mL Clear Glass Screw Cap Vial (850345P-500mg)

5 mL Amber Glass Screw Cap Vial (850345P-200mg)

5 mL Amber Glass Screw Cap Vial (850345P-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC