840475P

18:1 (Δ9-Cis) PG

Avanti Research^™ - A Croda Brand

• Sinonimo/i: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DOPG; PG(18:1(9Z)/18:1(9Z))
• Formula empirica (notazione di Hill): C₄₂H₇₈O₁₀PNa
• Numero CAS: 67254-28-8
• Peso molecolare: 797.03
• Numero MDL: MFCD33403202
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Descrizione: 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)
• Saggio: >99% (TLC)
• Stato: powder
• Confezionamento: pkg of 1 × 1 g (840475P-1g); pkg of 2 × 100 mg (840475P-200mg); pkg of 5 × 100 mg (840475P-500mg); pkg of 1 × 25 mg (840475P-25mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand
• Tipo di lipide: cardiolipins; phospholipids
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
• InChI: 1S/C42H79O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,39-40,43-44H,3-16,21-38H2,1-2H3,(H,47,48);/q;+1/p-1/b19-17-,20-18-;/t39?,40-;/m; IUVFCFQZFCOKRC-IPKKNMRRSA-M

Descrizione

Descrizione generale

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG has two hydroxyl groups in its head group. It is an anionic lipid.

Applicazioni

18:1 (Δ9-Cis) PG has been used:

• in the preparation of giant unilamellar vesicle (GUV)
• in the preparation 200 nm large unilamellar vesicles (LUV)
• as a supplement in native macrophage membranes to generate membrane liposomes with an artificially modified electrical charge

Azioni biochim/fisiol

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.

Confezionamento

5 mL Clear Glass Sealed Ampule (840475P-200mg)

5 mL Clear Glass Sealed Ampule (840475P-25mg)

5 mL Clear Glass Sealed Ampule (840475P-500mg)

60 mL Amber Wide Mouth Screw Cap Glass Bottle (840475P-1g)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3