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840035P

Avanti

18:1 PS (DOPS)

Avanti Polar Lipids

Sinonimo/i:

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); DOPS; PS(18:1(9Z)/18:1(9Z))

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About This Item

Formula empirica (notazione di Hill):
C42H77NO10PNa
Numero CAS:
Peso molecolare:
810.03
Codice UNSPSC:
51191904
NACRES:
NA.25

Saggio

>99% (TLC)

Forma fisica

powder

Confezionamento

pkg of 1 × 10 mg (840035P-10mg)
pkg of 2 × 100 mg (840035P-200mg)
pkg of 5 × 100 mg (840035P-500mg)
pkg of 1 × 25 mg (840035P-25mg)

Produttore/marchio commerciale

Avanti Polar Lipids

Tipo di lipide

cardiolipins
phospholipids

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C42H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b19-17-,20-18-;/t38-,39+;/m1./s1
KPHZNDUWYZIXFY-YORIBCANSA-M

Descrizione generale

DOPS is an excellent substitute for the naturally occurring Brain PS. It has similar physical properties and is more stable to oxidation. DOPS has been used, along with DOPC and DOPE, in lipid mixtures to mimic platelet membranes for coagulation studies.
Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.

Applicazioni

18:1 PS (DOPS) has been used:
  • in liposomes (multi-lamellar vesicles) preparation
  • as a component in incubation buffer to measure exosomes associated procoagulant activity
  • in the preparation of lipid vesicles

Azioni biochim/fisiol

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It has the ability to cross the blood-brain barrier. It plays a key role in the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.

Confezionamento

5 mL Clear Glass Sealed Ampule (840035P-10mg)
5 mL Clear Glass Sealed Ampule (840035P-200mg)
5 mL Clear Glass Sealed Ampule (840035P-25mg)
5 mL Clear Glass Sealed Ampule (840035P-500mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Proteomics profiling of plasma exosomes in epithelial ovarian cancer: A potential role in the coagulation cascade, diagnosis and prognosis
Zhang W, et al.
International journal of oncology, 54(5), 1719-1733 (2019)
Toshihiko Oka et al.
Langmuir : the ACS journal of surfaces and colloids, 33(43), 12487-12496 (2017-10-03)
Electrostatic interactions (EIs) play important roles in the structure and stability of inverse bicontinuous cubic (QII) phases of lipid membranes. We examined the effect of pH on the phase of dioleoylphosphatidylserine (DOPS)/monoolein (MO) membranes at low ionic strengths using small-angle
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Benaziz L, et al.
Journal of Colloid and Interface Science, 238(1), 48-53 (2001)
Kabir H Biswas et al.
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The pathway of vesicle adsorption onto a solid support depends on the material composition of the underlying support, and there is significant interest in developing material-independent strategies to modulate the spectrum of vesicle-substrate interactions on a particular surface. Herein, using

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