394963

N,N-Dimethylformamide dimethyl acetal

for GC derivatization, LiChropur^™

• Sinonimo/i: 1,1-Dimethoxy-N,N-dimethylmethylamine, 1,1-Dimethoxytrimethylamine
• Formula condensata: (CH₃)₂NCH(OCH₃)₂
• Numero CAS: 4637-24-5
• Peso molecolare: 119.16
• Beilstein: 506020
• Numero CE: 225-063-3
• Numero MDL: MFCD00008482
• Codice UNSPSC: 12000000
• ID PubChem: 24864631
• NACRES: NA.22

Proprietà

• Grado: for GC derivatization
• Livello qualitativo: 100
• Saggio: >95%
• Forma fisica: liquid
• Qualità: LiChropur^™
• Impiego in reazioni chimiche: reagent type: derivatization reagent; reaction type: Acylations; reagent type: derivatization reagent; reaction type: Esterifications
• tecniche: gas chromatography (GC): suitable
• Indice di rifrazione: n20/D 1.396 (lit.)
• P. eboll.: 102-103 °C/720 mmHg (lit.)
• Densità: 0.897 g/mL at 25 °C (lit.)
• Stringa SMILE: COC(OC)N(C)C
• InChI: 1S/C5H13NO2/c1-6(2)5(7-3)8-4/h5H,1-4H3; ZSXGLVDWWRXATF-UHFFFAOYSA-N

Descrizione

Descrizione generale

Esterate M (N,N-Dimethylformamide dimethyl acetal, DMFDMA) is an methylating reagent. It has been used in methyl esterification of carboxylic acid and also in one-step derivatization of amino acids into N,N-Dimethylaminomethylene methyl esters.

Applicazioni

It may be used in methylation of heterocyclic compounds which contains SH, NH, OH groups such as benzimidazole, naphth[2,3-c]imidazole, imidazo[4,5-c]-pyridine, purine, pyridine, pyrimidine, pyridazine and s-triazolo[4,3-b]pyridazine. It was used as derivatizing agent in a study to determine cocaine and benzoyl ecgonine in urine using GC with on-column alkylation.

Suitable for the derivatization of primary sulfonamides and trifluoroacetic acid.

Used in the preparation of formamidine derivatives, which are synthetic intermediates.

Used to catalyze the coupling of epoxides with carbon dioxide under solvent free conditions leading to cyclic carbonates.

Altre note

Reagent for n-dimethylaminomethylene and methyl esters.

Note legali

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS05,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H317,H318,H332
• Consigli di prudenza: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Sens. 1
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 42.8 °F
• Punto d’infiammabilità (°C): 6 °C
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter