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1576708

USP

Propylene glycol

United States Pharmacopeia (USP) Reference Standard

Sinônimo(s):

1,2-Propanediol, Propylene glycol

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About This Item

Fórmula linear:
CH3CH(OH)CH2OH
Número CAS:
57-55-6
Peso molecular:
76.09
Beilstein:
1340498
Número MDL:
MFCD00064272
Código UNSPSC:
41116107
ID de substância PubChem:
329750993
NACRES:
NA.24

grau

pharmaceutical primary standard

densidade de vapor

2.62 (vs air)

pressão de vapor

0.08 mmHg ( 20 °C)

família API

propylene glycol

temperatura de autoignição

779 °F

Lim. expl.

12.5 %

fabricante/nome comercial

USP

índice de refração

n20/D 1.432 (lit.)

p.e.

187 °C (lit.)

pf

−60 °C (lit.)

densidade

1.036 g/mL at 25 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

cadeia de caracteres SMILES

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

chave InChI

DNIAPMSPPWPWGF-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Propylene glycol USP reference standard intended for use in specified quality tests and assays.

Also used to prepare standard stock, standard, sample, system suitability, and sensitivity solution for assay and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Propylene Glycol Dilaurate
  • Phenytoin Sodium Injection
  • Hydroxypropyl Betadex
  • Butylene Glycol

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

219.2 °F - closed cup

Ponto de fulgor (°C)

104 °C - closed cup

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SAFC

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J S LaKind et al.
Critical reviews in toxicology, 29(4), 331-365 (1999-08-18)
The purpose of this article is to review and interpret the scientific literature on the mammalian toxicity of ethylene glycol (EG) and propylene glycol (PG), with the goal of comparing the toxicity of the two chemicals. This type of review
Holger Lessmann et al.
Contact dermatitis, 53(5), 247-259 (2005-11-15)
In the several publications reviewed in this article, propylene glycol (PG; 1,2-propylene glycol) is described as a very weak contact sensitizer, if at all. However, particular exposures to PG-containing products might be associated with an elevated risk of sensitization. To
Li Wang et al.
Hepatology (Baltimore, Md.), 61(2), 486-496 (2014-09-10)
Defective autophagy is implicated in the pathogenesis of nonalcoholic fatty liver diseases (NAFLD) through poorly defined mechanisms. Cardiolipin is a mitochondrial phospholipid required for bioenergetics and mitophagy from yeast to mammals. Here we investigated a role for ALCAT1 in the
Janina Seubert et al.
PloS one, 9(5), e98347-e98347 (2014-05-31)
Scented cosmetic products are used across cultures as a way to favorably influence one's appearance. While crossmodal effects of odor valence on perceived attractiveness of facial features have been demonstrated experimentally, it is unknown whether they represent a phenomenon specific
J O Funk et al.
Contact dermatitis, 31(4), 236-241 (1994-10-01)
Evaluation of dermatitis associated with propylene glycol application or ingestion remains a challenge. The research dealing with skin reactions to propylene glycol is revisited and new aspects for future research are outlined. Based on literature review and our own observations
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Protocolos

GC Analysis of Glycols on Nukol™

99%; Glycerol, ≥99.5%; Tetraethylene glycol, 99%

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