1009005
USP
Acetylcysteine
United States Pharmacopeia (USP) Reference Standard
Sinônimo(s):
N-Acetyl-L-cysteine, LNAC, NAC
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About This Item
Fórmula linear:
HSCH2CH(NHCOCH3)CO2H
Número CAS:
Peso molecular:
163.19
Beilstein:
1724426
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24
Produtos recomendados
grau
pharmaceutical primary standard
família API
acetylcysteine
fabricante/nome comercial
USP
pf
106-108 °C (lit.)
aplicação(ões)
pharmaceutical (small molecule)
formato
neat
temperatura de armazenamento
2-8°C
cadeia de caracteres SMILES
CC(=O)N[C@@H](CS)C(O)=O
InChI
1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
chave InChI
PWKSKIMOESPYIA-BYPYZUCNSA-N
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Descrição geral
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Aplicação
Acetylcysteine USP reference standard intended for use in specified compendial tests and assays.
Also used to prepare standard stock and standard solution for assay by using the liquid chromatography method in conjunction with uv detector according to the given below monographs of United States Pharmacopeia (USP):
Also used to prepare standard stock and standard solution for assay by using the liquid chromatography method in conjunction with uv detector according to the given below monographs of United States Pharmacopeia (USP):
- Acetylcysteine Solution
- Acetylcysteine
- Acetylcysteine Compounded Solution
Ações bioquímicas/fisiológicas
Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.
Nota de análise
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Outras notas
Sales restrictions may apply.
produto relacionado
Nº do produto
Descrição
Preços
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2
Código de classe de armazenamento
13 - Non Combustible Solids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
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Acetylcysteine Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 27(3), 82-82 (2020)
Yuval Samuni et al.
Biochimica et biophysica acta, 1830(8), 4117-4129 (2013-04-27)
N-acetylcysteine (NAC) has been in clinical practice for several decades. It has been used as a mucolytic agent and for the treatment of numerous disorders including paracetamol intoxication, doxorubicin cardiotoxicity, ischemia-reperfusion cardiac injury, acute respiratory distress syndrome, bronchitis, chemotherapy-induced toxicity
Anna M Sadowska
Therapeutic advances in respiratory disease, 6(3), 127-135 (2012-03-01)
To develop an efficient therapy for chronic obstructive pulmonary disease (COPD), N-acetylcysteine (NAC) has been tested as a medication that can suppress various pathogenic processes in this disease. NAC is a thiol compound, which provides sulfhydryl groups. NAC can act
Javed Akhter et al.
American journal of cancer research, 4(5), 495-507 (2014-09-19)
Compared to current treatment for pseudomyxoma peritonei (PMP), the extraction of solubilised mucin through peritoneal catheter can be minimally invasive. However, mucin has variable appearance that may influence mucolysis. Hence, we investigated the mucolysis of 36 mucin samples with a
Gaurav Sharma et al.
Nanotoxicology, 8(6), 663-675 (2013-07-11)
Spontaneous agglomeration of engineered nanoparticles (ENPs) is a common problem in cell culture media which can confound interpretation of in vitro nanotoxicity studies. The authors created stable agglomerates of iron oxide nanoparticles (IONPs) in conventional culture medium, which varied in
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