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A9165

Sigma-Aldrich

N-Acetyl-L-cysteine

≥99% (TLC), suitable for cell culture, BioReagent

Sinônimo(s):

LNAC, NAC

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About This Item

Fórmula linear:
HSCH2CH(NHCOCH3)CO2H
Número CAS:
616-91-1
Peso molecular:
163.19
Beilstein:
1724426
Número CE:
210-498-3
Número MDL:
MFCD00004880
Código UNSPSC:
12352209
ID de substância PubChem:
24891402
NACRES:
NA.26

Nome do produto

N-Acetyl-L-cysteine, BioReagent, suitable for cell culture

linha de produto

BioReagent

Nível de qualidade

200

Ensaio

≥99% (TLC)

Formulário

powder

técnica(s)

cell culture | mammalian: suitable

cor

white to off-white

pf

106-108 °C (lit.)

solubilidade

H2O: 100 mg/mL (with heating)

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC(=O)N[C@@H](CS)C(O)=O

InChI

1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

chave InChI

PWKSKIMOESPYIA-BYPYZUCNSA-N

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Aplicação

N-Acetyl-L-cysteine has been used as a component of intestinal basal medium for the culture of mouse intestinal stem cells and also as a component of expansion medium.

Ações bioquímicas/fisiológicas

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

Outras notas

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Aplicação

Nº do produto
Descrição
Preços

geralmente comprado junto com este produto

Nº do produto
Descrição
Preços

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H319

Classificações de perigo

Eye Irrit. 2

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
WXBD6569V
WXBD5529V
WXBD4741V
SLCJ1628
WXBD3714V

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Sigma-Aldrich

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Sigma-Aldrich

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Acetylcysteine European Pharmacopoeia (EP) Reference Standard

A0150000

Acetylcysteine

N-Acetyl-L-cysteine Mucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock.

Millipore

106425

N-Acetyl-L-cysteine

Colagenase powder, Suitable for the digestion and isolation of physiologically active pancreatic islet cells, suitable for cell culture

Sigma-Aldrich

C9407

Colagenase

Derivation and long-term expansion of human endometrial and decidual organoids
Margherita Turco
Protocol Exchange, 2639-2644 (2017)
Isolation, Culture, and Maintenance of Mouse Intestinal Stem Cells
Kevin P. O?Rourke
Bio-protocol, 6(4), e1733-e1733 (2016)
Jing Xie et al.
Bone research, 7, 23-23 (2019-10-28)
Osteoarthritis (OA) is an age-related disorder that is strongly associated with chondrocyte senescence. The causal link between disruptive PTEN/Akt signaling and chondrocyte senescence and the underlying mechanism are unclear. In this study, we found activated Akt signaling in human OA
Meritxell Huch et al.
Nature, 494(7436), 247-250 (2013-01-29)
The Wnt target gene Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) marks actively dividing stem cells in Wnt-driven, self-renewing tissues such as small intestine and colon, stomach and hair follicles. A three-dimensional culture system allows long-term clonal expansion of single Lgr5(+) stem
Suzanne M Cloonan et al.
Journal of medicinal chemistry, 58(11), 4494-4505 (2015-05-12)
Ruthenium polypyridyl complexes show great promise as new photodynamic therapy (PDT) agents. However, a lack of detailed understanding of their mode of action in cells poses a challenge to their development. We have designed a new Ru(II) PDT candidate that
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Mitochondrial Stress and ROS

Oxidative stress is mediated, in part, by reactive oxygen species produced by multiple cellular processes and controlled by cellular antioxidant mechanisms such as enzymatic scavengers or antioxidant modulators. Free radicals, such as reactive oxygen species, cause cellular damage via cellular.

3D Organoid Culture: New In Vitro Models of Development and Disease

rganoid culture products to generate tissue and stem cell derived 3D brain, intestinal, gut, lung and cancer tumor organoid models.

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Chromatograms

application for HPLC

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